Ireland· IE-PA-EU/1/96/027/007

HYCAMTIN 1 mg hard capsules

A topotecan product containing topotecan hydrochloride, registered in Ireland by Sandoz Pharmaceuticals d.d.. The same ATC class is registered in 15 of our 19 countries.

ATC L01CE01

Checked against HPRA (Ireland) on September 28, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about topotecan hydrochlorideAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Topotecan is registered in 15 of 19 countries.

Countries holding a registration under ATC L01CE01 (topotecan), each read from that country’s own register.

This record: Ireland, from HPRA (Ireland)
9 of them publish a price we can compare per daily dose

Search topotecan products by name

Topotecan · ATC L01CE01

15 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Germany
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of topotecan costs, country by country.

Normalised to the WHO defined daily dose (1 mg), so markets compare like for like.

1 market with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Topotecan · price per daily dose (1 mg)

USD · FX 28 Sept 2026

CH Switzerland$80.29

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

HPRA (Ireland)

Active substance: Topotecan hydrochloride
Manufacturer: Sandoz Pharmaceuticals d.d.
Country: Ireland (IE)
ATC code: L01CE01
ATC class: Topotecan
Defined daily dose: 1 mg, O
Reimbursed: Not published by this register
Source register: HPRA (Ireland)
Last checked: September 28, 2026

Packs & prices · 1

ie_pa_number
EU/1/96/027/007

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

348 interactions on record for topotecan.

Graded by severity as the source publishes them — 31 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check topotecan against other medicines How interaction checks work

Topotecan · interactions on record

348 records

31 severe
277 moderate
16 minor
24 info

Most severe, free to view

CisplatinL01XA01severe
CarboplatinL01XA02severe
OxaliplatinL01XA03severe
RolapitantA04AD14moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Topotecan in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All topotecan products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Topotecan Accord, Topotecan Ebewe
Belgium · Topotecan Accord Healthcare
Bulgaria · Топотекан Акорд
Cyprus · Topotecan Accord, Topotecan Venus
Czechia · Topotecan Accord
Germany · Topotecan Accord, Topotecan Hexal
Denmark · Topotecan "ebewe", Topotecan Accord
Estonia · Topotecan Accord
Spain · Topotecán Accord
Finland · Topotecan Accord, Topotecan Ebewe
France · Topotecane Accord
United Kingdom (Northern Ireland) · Topotecan Accord Healthcare, Topotecan Sandoz
Greece · Topocan, Topotecan Accord
Croatia · Topotekan Alpha-Medical
Hungary · Topotecan Accord
Iceland · Hycamtin, Potactasol
Italy · Topotecan Ahcl
Liechtenstein · Hycamtin, Hycamtin 4 Mg Powder For Concentrate For Solution For Infusion
Lithuania · Topotecan Accord
Luxembourg · Topotecan Accord Healthcare
Latvia · Topotecan Ahcl
Netherlands · Topotecan Accord, Topotecan Hikma
Norway · Hycamtin, Potactasol
Poland · Topotecanum Accord
Portugal · Topotecano Accord, Topotecano Azevedos
Romania · Topotecan Accord
Sweden · Topotecan Accord, Topotecan Ebewe
Slovenia · Topotekan Accord
Slovakia · Topotecan Accord

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/d03e8522-e1e2-4fc9-8d1c-ffdf518502bd
GET /v1/drugs/d03e8522-e1e2-4fc9-8d1c-ffdf518502bd?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Capsule, hard",
  "routes": [
    "Oral use"
  ],
  "source": "hpra",
  "atc_all": [
    "L01CE01"
  ],
  "strength": null,
  "pa_number": "EU/1/96/027/007",
  "substances": [
    "Topotecan hydrochloride"
  ],
  "legal_basis": "Full application (Article 8(3) of Directive No 2001/83/EC)",
  "market_info": "Unknown",
  "authorised_at": "18/03/2008",
  "dispensing_status": "Product subject to prescription which may not be renewed (A)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": null
}

API reference MCP server Plans

See everything about topotecan.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console