Poland· PL-100536740
Vagifem
A estradiol product containing estradiolum, registered in Poland by Delfarma Sp. z o.o.. The same ATC class is registered in 13 of our 19 countries.
Checked against URPL (Poland) on
Informational only — not a medical device.
Where it is registered
Estradiol is registered in 13 of 19 countries.
Countries holding a registration under ATC G03CA03 (estradiol), each read from that country’s own register.
- This record: Poland, from URPL (Poland)
- 9 of them publish a price we can compare per daily dose
Estradiol · ATC G03CA03
13 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Statesprice
Price per daily dose
What a daily dose of estradiol costs, country by country.
Normalised to the WHO defined daily dose (0.3 mg), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Estradiol · price per daily dose (0.3 mg)
USD · FX 28 Sept 2026
- CH Switzerland$0.11
The record
At a glance
URPL (Poland)- Active substance
- Estradiolum
- Manufacturer
- Delfarma Sp. z o.o.
- Country
- Poland (PL)
- ATC code
- G03CA03
- ATC class
- Estradiol
- Defined daily dose
- 0.3 mg, N
- Reimbursed
- Not published by this register
- Source register
- URPL (Poland)
- Last checked
- September 27, 2026
Packs & prices · 2
- gtin05909991599454
- gtin05909991599461
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
328 interactions on record for estradiol.
Graded by severity as the source publishes them — 7 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Estradiol · interactions on record
328 records
- 7 severe
- 177 moderate
- 3 minor
- 131 info
Most severe, free to view
- Tranexamic acidB02AA02severe
- HeminB06AB01severe
- CarfilzomibL01XG02severe
- CarfilzomibL01XX45severe
10 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Estradiol in 17 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- SwedenEstradiol SUN 10 mikrogram VaginaltablettSun Pharmaceutical Industries Europe B.V.
- IrelandEstradiol SUN 10 micrograms vaginal tabletsSun Pharmaceutical Industries Europe B.V.
- United StatesYuvafemAvKARE
- NetherlandsVagifem 10 microgram, filmomhulde tabletten voor vaginaal gebruikNovo Nordisk A.S.
- NorwayVagidonnaSandoz - København
- SpainVAGIRUX 10 MICROGRAMOS COMPRIMIDOS VAGINALESGedeon Richter Plc.
- SwitzerlandVagifem 10 µg, VaginaltablettenNovo Nordisk Pharma AG
- CanadaVAGIFEM 10NOVO NORDISK CANADA INC
Authorised across Europe · EMA
The same active substance is authorised in 29 EEA countries. Names it is sold under:
- Austria · Estrofem, Femseven
- Belgium · Estradiol Besins, Estrofem
- Bulgaria · Естрогел, Естрофем
- Cyprus · Vagifem
- Czechia · Estradiol Besins, Estrofem
- Germany · Estradiol Fem Jenapharm, Estrifam
- Denmark · Divigel, Ercostrol
- Estonia · Divigel, Estradiol Besins
- Spain · Divigel, Estradiol Besins
- Finland · Divigel, Estradot
- France · Dermestril, Dermestril Septem
- United Kingdom (Northern Ireland) · Elleste, Elleste Solo Mx
- Greece · Vagifem
- Croatia · Estradiol Besins, Estrofem
- Hungary · Estradiol Besins, Estrofem
- Ireland · Divigel, Estradiol Sun
- Iceland · Estring, Estrofem
- Italy · Dermestril, Femseven
- Lithuania · Divigel, Estradiol Besins
- Luxembourg · Dermestril 100, Dermestril 25
- Latvia · Estradiol Besins, Estrofem
- Malta · Oestrogel Pump-Pack, Vagifem
- Netherlands · Cetura, Estradiol Sandoz
- Norway · Estradot, Estrogel
- Portugal · Dermestril, Estradot
- Romania · Estradiol Besins
- Sweden · Divigel, Estradiol Besins
- Slovenia · Estradiol Besins, Vagifem
- Slovakia · Estradiol Besins, Estrofem
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of URPL (Poland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/cf7f0998-58f9-4dbe-ac25-fb376fe07ff4 GET /v1/drugs/cf7f0998-58f9-4dbe-ac25-fb376fe07ff4?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tabletki dopochwowe",
"source": "urpl",
"strength": "10 mcg",
"packaging": "05909991599454 ¦ Rp ¦ 166796\n18 tabl.\n05909991599461 ¦ Rp ¦ 166797\n24 tabl.",
"substance": "Estradiolum/10 mcg",
"common_name": "Estradiolum",
"pl_product_id": "100536740",
"pozwolenie_nr": "142/26",
"auth_procedure": "IR",
"authorisation_validity": "2031-04-21"
}See everything about estradiol.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.