Italy· 022593204
BRUFEN
A ibuprofen product containing ibuprofene, registered in Italy by VIATRIS ITALIA S.R.L., on the national reimbursement list. The same ATC class is registered in 12 of our 19 countries.
Checked against AIFA (Italy) on
Informational only — not a medical device.
Where it is registered
Ibuprofen is registered in 12 of 19 countries.
Countries holding a registration under ATC M01AE01 (ibuprofen), each read from that country’s own register.
- This record: Italy, from AIFA (Italy)
- 8 of them publish a price we can compare per daily dose
Ibuprofen · ATC M01AE01
12 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
Price per daily dose
What a daily dose of ibuprofen costs, country by country.
Normalised to the WHO defined daily dose (1.2 g), the median price runs from $0.28 in Italy to $1.24 in Switzerland — a ×4.4 gap.
- Italy: $0.28 per daily dose (median across products in the class)
- Public list prices, converted to USD at the rate date shown
Ibuprofen · price per daily dose (1.2 g)
USD · FX 28 Sept 2026
- CH Switzerland$1.24
- IT Italy$0.28
The record
At a glance
AIFA (Italy)- Active substance
- Ibuprofene
- Manufacturer
- VIATRIS ITALIA S.R.L.
- Country
- Italy (IT)
- ATC code
- M01AE01
- ATC class
- Ibuprofen
- Defined daily dose
- 1.2 g, O
- Reimbursed
- Yes
- Source register
- AIFA (Italy)
- Last checked
- September 28, 2026
Packs & prices · 1
1 priced- aic022593204"400 MG COMPRESSE RIVESTITE" 30 COMPRESSE IN BLISTER PVC/PVDC/ALUEUR 2.78
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
886 interactions on record for ibuprofen.
Graded by severity as the source publishes them — 71 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Ibuprofen · interactions on record
886 records
- 71 severe
- 306 moderate
- 15 minor
- 413 info
Most severe, free to view
- DicoumarolB01AA01severe
- WarfarinB01AA03severe
- DalteparinB01AB04severe
- EnoxaparinB01AB05severe
81 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Ibuprofen in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaNUROFENReckitt Benckiser (Czech Republic), spol. s r.o., Praha
- NetherlandsAlbert Heijn Ibuprofen 400 mg, omhulde tablettenSameko Farma B.V.
- BelgiumBuprophar 400 mgTeva Pharma Belgium
- FranceADVIL 400 mg, comprimé enrobéHALEON FRANCE
- IrelandNurofen Express Maximum Strength 400 mg tabletsPCO Manufacturing Ltd.
- SpainESPIDIDOL 400 mg COMPRIMIDOS RECUBIERTOSZambon S.A.U.
- FinlandNurofenLaboratorios Liade S.A.
- United States365 whole foods market ibuprofenWhole Foods Market, INC.
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Adolorin Ibuforte Direkt, Adolorini Direkt
- Belgium · Brufen, Brufen Forte
- Bulgaria · Ibuprofen Nutra Essential, Ibuprofen Pharmdedict
- Cyprus · Algovil, Algovil Rapid
- Czechia · Brufen, Brufen Rapidcaps
- Germany · Aktren Forte, Ambaprofen
- Denmark · Brufen, Brufen Retard
- Estonia · Brufen, Dolgit
- Spain · Apirofeno, Aragel
- Finland · Burana, Burana Mustaherukka
- France · Advil, Advilcaps
- United Kingdom (Northern Ireland) · 3 Months Ibuprofen Strawberry Flavour, 3 Months Plus Strawberry Flavour
- Greece · Advil, Advil Forte
- Croatia · Blokmax, Blokmax Forte
- Hungary · Advil Ultra, Advil Ultra Forte
- Ireland · Actiprofen, Advil Liquid
- Iceland · Alvofen Express, Alvofen Junior
- Liechtenstein · Ibuprofen Gen.Orph, Pedea
- Lithuania · Brufen, Deliprom
- Luxembourg · Brufen, Brufen Forte
- Latvia · Brufen, Ibugard
- Malta · Algofren, Brufen
- Netherlands · Advil, Advil Reliva Forte Liquid Caps
- Norway · Brufen Retard, Ibumax
- Poland · Axoprofen, Axoprofen Forte
- Portugal · Algik, Azevedos
- Romania · Adagin, Adagin Forte
- Sweden · Brufen, Brufen Retard
- Slovenia · Brufen, Brufen Retard
- Slovakia · Brufen, Brufen Instant
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of AIFA (Italy). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/cd95af55-ff00-42f9-9801-85f92a138ab3 GET /v1/drugs/cd95af55-ff00-42f9-9801-85f92a138ab3?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"pack": "\"400 MG COMPRESSE RIVESTITE\" 30 COMPRESSE IN BLISTER PVC/PVDC/ALU",
"source": "aifa",
"currency": "EUR",
"substance": "Ibuprofene",
"reference_pack": "30 UNITA' 400 MG - USO ORALE",
"public_price_eur": 2.78,
"ssn_reference_price_eur": 4.64
}See everything about ibuprofen.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.