United States· US:59779-367_16f6831d-bed1-40c6-84f0-065b2d67f755
Nighttime Sleep Aid
A diphenhydramine product containing diphenhydramine hcl, registered in United States by CVS Pharmacy. The same ATC class is registered in 6 of our 19 countries.
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
Where it is registered
Diphenhydramine is registered in 6 of 19 countries.
Countries holding a registration under ATC D04AA32 (diphenhydramine), each read from that country’s own register.
- This record: United States, from FDA National Drug Code directory (United States)
- 4 of them publish a price we can compare per daily dose
Diphenhydramine · ATC D04AA32
6 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Finlandprice
- United Kingdom
- United Statesprice
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- Diphenhydramine HCl
- Manufacturer
- CVS Pharmacy
- Country
- United States (US)
- ATC code
- D04AA32
- ATC class
- Diphenhydramine
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 12, 2026
Packs & prices · 3
- ndc1159779367082 BLISTER PACK in 1 CARTON (59779-367-08) / 12 TABLET, FILM COATED in 1 BLISTER PACK
- ndc1159779367121 BOTTLE in 1 CARTON (59779-367-12) / 100 TABLET, FILM COATED in 1 BOTTLE
- ndc1159779367201 BOTTLE, PLASTIC in 1 CARTON (59779-367-20) / 225 TABLET, FILM COATED in 1 BOTTLE, PLASTIC
Regulatory notes
Interactions
6 interactions on record for diphenhydramine.
Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Diphenhydramine · interactions on record
6 records
- 2 severe
- 4 moderate
Most severe, free to view
- Sodium oxybateN01AX11severe
- Sodium oxybateN07XX04severe
- FlibanserinG02CX02moderate
- ApomorphineG04BE07moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Diphenhydramine in 11 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CanadaALLERGY FORMULAJUNO OTC INC
- United KingdomAdult Meltus Night Time syrupSSL International Plc
- GermanyBetadorm-DRecordati Pharma Gmbh
- BelgiumAzaron 20 mg/g LotionPerrigo Belgium
- NorwayDiphenhydramine eonEon Labs
- SwitzerlandBenocten, TablettenMedinova AG
- PolandLuminastilAflofarm Farmacja Polska Sp. z o.o.
- SpainDIFENHIDRAMINA OMEGA PHARMA 50 MG COMPRIMIDOSOmega Pharma España, S.A.
Authorised across Europe · EMA
The same active substance is authorised in 20 EEA countries. Names it is sold under:
- Austria · Calmaben, Dermodrin
- Belgium · Nustasium, R Calm
- Bulgaria · Дермодрин, Калмабен
- Czechia · Psilo-Balsam
- Germany · Betadorm-D, Diphenhydramin Hevert
- Denmark · Benylan, Coldycof
- Spain · Neosayomol, Soñodor
- United Kingdom (Northern Ireland) · Almus Max Strength Sleep Aid, Asda Night Time Sleep Aid
- Hungary · Supraderm
- Ireland · Nytol One-A-Night
- Iceland · Benylan
- Italy · Allergan
- Lithuania · Psilo-Balsam
- Luxembourg · Nustasium
- Latvia · Pretniezes, Psilo-Balsam
- Poland · Luminastil, Nodisen
- Portugal · Benaderma, Benergina
- Romania · Calmaben, Dermodrin
- Sweden · Desentol
- Slovakia · Calmaben, Psilo-Balsam
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/cd1cfcdd-1d3c-4d49-af8e-4e23b420e208 GET /v1/drugs/cd1cfcdd-1d3c-4d49-af8e-4e23b420e208?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"unii": {
"unii": "TC2D6JAD40",
"rxcui": "1362",
"inchikey": "PCHPORCSPXIHLZ-UHFFFAOYSA-N",
"display_name": "DIPHENHYDRAMINE HYDROCHLORIDE",
"substance_type": "chemical",
"ingredient_type": "INGREDIENT SUBSTANCE"
},
"route": "ORAL",
"livertox": {
"summary": null,
"livertox_id": null,
"hepatotoxicity_score": 5
},
"spl_meta": {
"2201d5c0-bd51-47a7-9775-916b18573623": {
"match": "brand_token",
"title": "NIGHTTIME (ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE) SOLUTION [PUBLIX SUPER MARKETS INC]",
"spl_version": "8",
"published_date": "2026-05-25"
}
},
"productid": "59779-367_16f6831d-bed1-40c6-84f0-065b2d67f755",
"productndc": "59779-367",
"dosage_form": "TABLET, FILM COATED",
"dea_schedule": null,
"product_type": "HUMAN OTC DRUG",
"substance_name": "DIPHENHYDRAMINE HYDROCHLORIDE",
"proprietary_name": "Nighttime Sleep Aid",
"active_ingred_unit": "mg/1",
"application_number": "M010",
"marketing_category": "OTC MONOGRAPH DRUG",
"nonproprietary_name": "Diphenhydramine HCl",
"start_marketing_date": "20000610",
"active_numerator_strength": "25"
}See everything about diphenhydramine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.