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United Kingdom· GB-APID-4575811000001103

Histergan 2% cream

A diphenhydramine product containing diphenhydramine, registered in United Kingdom by Norma Chemicals Ltd. The same ATC class is registered in 6 of our 19 countries.

ATC D04AA32

Checked against NHS dm+d (United Kingdom) on

Informational only — not a medical device.

SOURCE REGISTER · GBNHS dm+d (United Kingdom)normalisedHistergan 2% creamATCD04AA32REGISTER NO.GB-APID-4575811000001…PACKS LISTED2CHECKEDSeptember 13, 2026

Where it is registered

Diphenhydramine is registered in 6 of 19 countries.

Countries holding a registration under ATC D04AA32 (diphenhydramine), each read from that country’s own register.

  • This record: United Kingdom, from NHS dm+d (United Kingdom)
  • 4 of them publish a price we can compare per daily dose

Diphenhydramine · ATC D04AA32

6 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Finlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

NHS dm+d (United Kingdom)
Active substance
Diphenhydramine
Manufacturer
Norma Chemicals Ltd
Country
United Kingdom (GB)
ATC code
D04AA32
ATC class
Diphenhydramine
Reimbursed
Not published by this register
Source register
NHS dm+d (United Kingdom)
Last checked
September 13, 2026

Packs & prices · 2

  • gtin
    05060676350064
  • gtin
    5034593027200

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

6 interactions on record for diphenhydramine.

Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Diphenhydramine · interactions on record

6 records

  • 2 severe
  • 4 moderate

Most severe, free to view

  • Sodium oxybateN01AX11severe
  • Sodium oxybateN07XX04severe
  • FlibanserinG02CX02moderate
  • ApomorphineG04BE07moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Diphenhydramine in 11 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All diphenhydramine products

Authorised across Europe · EMA

The same active substance is authorised in 19 EEA countries. Names it is sold under:

  • Austria · Calmaben, Dermodrin
  • Belgium · Nustasium, R Calm
  • Bulgaria · Дермодрин, Калмабен
  • Czechia · Psilo-Balsam
  • Germany · Betadorm-D, Diphenhydramin Hevert
  • Denmark · Benylan, Coldycof
  • Spain · Neosayomol, Soñodor
  • Hungary · Supraderm
  • Ireland · Nytol One-A-Night
  • Iceland · Benylan
  • Italy · Allergan
  • Lithuania · Psilo-Balsam
  • Luxembourg · Nustasium
  • Latvia · Pretniezes, Psilo-Balsam
  • Poland · Luminastil, Nodisen
  • Portugal · Benaderma, Benergina
  • Romania · Calmaben, Dermodrin
  • Sweden · Desentol
  • Slovakia · Calmaben, Psilo-Balsam

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/cc5d93b4-89c7-498c-b5a5-579b403b1ea7
GET /v1/drugs/cc5d93b4-89c7-498c-b5a5-579b403b1ea7?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "apid": "4575811000001103",
  "desc": "Histergan 2% cream (Norma Chemicals Ltd)",
  "form": "Cutaneous cream",
  "vpid": "41895711000001105",
  "source": "dmd",
  "vtm_id": "775626005",
  "strength": "20 mg",
  "substance": "Diphenhydramine",
  "ingredient": "Diphenhydramine hydrochloride",
  "supplier_code": "2079901000001100"
}

See everything about diphenhydramine.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.