Netherlands· NL-cd08321d2bc1

Dualkopt 20 mg/ml + 5 mg/ml, oogdruppels, oplossing

A timolol, kombinationen product containing dorzolamidehydrochloride + timololmaleaat, registered in Netherlands by Laboratoires Théa. The same ATC class is registered in 12 of our 19 countries.

ATC S01ED51

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about dorzolamidehydrochloride + timololmaleaatAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Timolol, kombinationen is registered in 12 of 19 countries.

Countries holding a registration under ATC S01ED51 (timolol, kombinationen), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
8 of them publish a price we can compare per daily dose

Search timolol, kombinationen products by name

Timolol, kombinationen · ATC S01ED51

12 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)

Active substance: DORZOLAMIDEHYDROCHLORIDE + TIMOLOLMALEAAT
Manufacturer: Laboratoires Théa
Country: Netherlands (NL)
ATC code: S01ED51
ATC class: Timolol, Kombinationen
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
112681

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

1 interaction on record for timolol, kombinationen.

Mechanism, severity and management for each pair, from a commercially licensed source — included with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check timolol, kombinationen against other medicines How interaction checks work

Timolol, kombinationen · interactions on record

1 record

1 more interaction with mechanism and management, from a commercially licensed source.

Mechanism and what to do, in the interaction check

Interaction register. Grades as the source publishes them.

Same medicine, other countries

Timolol, kombinationen in 15 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All timolol, kombinationen products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Cosopt, Cosopt Sine
Belgium · Cosopt, Cosopt Sine Conservans
Bulgaria · Амиптифри, Дорзасопт
Cyprus · Cosopt, Cosopt Imulti
Czechia · Amiptic, Cosopt
Germany · Cosduo, Cosopt
Denmark · Cosopt, Cosopt Imulti Ukonserveret
Estonia · Cosopt, Dorzolamide/Timolol Elvim
Spain · Arzotim, Cosduo
Finland · Cosopt, Cosopt Sine
France · Atimiac, Cosidime
United Kingdom (Northern Ireland) · Codimaz, Cosopt
Greece · Apleona, Cosopt
Croatia · Apleona, Cosopt
Hungary · Cosopt, Cosopt Multi
Ireland · Cosopt, Cosopt Preservative-Free
Iceland · Arzotilol, Cosopt Sine
Italy · Betaclar, Cosopt
Lithuania · Cosopt, Cosopt Sine
Luxembourg · Cosopt, Cosopt Sine Conservans
Latvia · Amiptic, Amiptinon
Malta · Cosopt Preservative-Free
Norway · Apleona, Cosopt
Poland · Cosopt, Cosopt Pf
Portugal · Cosopt, Cosopt Multi
Romania · Cosopt, Cosopt Fără Conservant
Sweden · Cosopt, Cosopt Sine
Slovenia · Cosopt, Cosopt Brez Konzervansa
Slovakia · Cosopt, Cosopt Free

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/cc3e42e1-122f-454e-8876-33c8d3f94fdb
GET /v1/drugs/cc3e42e1-122f-454e-8876-33c8d3f94fdb?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Oogdruppels, oplossing",
  "route": "Oculair gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h112681_smpc.pdf",
  "strength": null,
  "atc_label": "Timolol, Combinations",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg112681",
  "excipients": [
    "HYDROXYETHYLCELLULOSE",
    "MANNITOL (D-) (E 421)",
    "NATRIUMHYDROXIDE (E 524)",
    "TRINATRIUMCITRAAT 2-WATER (E 331)",
    "WATER VOOR INJECTIE"
  ],
  "substances": [
    "DORZOLAMIDEHYDROCHLORIDE",
    "TIMOLOLMALEAAT"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h112681.pdf",
  "authorised_at": "2014/12/08",
  "procedure_number": "DE/H/3682/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "112681",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about timolol, kombinationen.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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