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Netherlands· NL-f2279362551e

Nuwiq 4000 IE poeder en oplosmiddel voor oplossing voor injectie

A coagulation factor viii product containing simoctocog alfa, registered in Netherlands by Octapharma AB. The same ATC class is registered in 11 of our 19 countries.

ATC B02BD02

Checked against CBG-MEB (Netherlands) on

Informational only — not a medical device.

SOURCE REGISTER · NLCBG-MEB (Netherlands)normalisedNuwiq 4000 IE poeder en oplosmiddel v…ATCB02BD02REGISTER NO.NL-f2279362551ePACKS LISTED1CHECKEDSeptember 29, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about simoctocog alfaAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Coagulation factor viii is registered in 11 of 19 countries.

Countries holding a registration under ATC B02BD02 (coagulation factor viii), each read from that country’s own register.

  • This record: Netherlands, from CBG-MEB (Netherlands)
  • 7 of them publish a price we can compare per daily dose
Search coagulation factor viii products by name

Coagulation factor viii · ATC B02BD02

11 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)
Active substance
SIMOCTOCOG ALFA
Manufacturer
Octapharma AB
Country
Netherlands (NL)
ATC code
B02BD02
ATC class
Coagulation factor VIII
Defined daily dose
1 TSD, E
Reimbursed
Not published by this register
Source register
CBG-MEB (Netherlands)
Last checked
September 29, 2026

Packs & prices · 1

  • cbg_meb_id
    EU/1/14/936

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

4 interactions on record for coagulation factor viii.

Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check coagulation factor viii against other medicinesHow interaction checks work

Coagulation factor viii · interactions on record

4 records

  • 2 severe
  • 2 moderate

Most severe, free to view

  • CarfilzomibL01XG02severe
  • CarfilzomibL01XX45severe
  • PegvaliaseA16AB19moderate
  • EmicizumabB02BX06moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Coagulation factor viii in 14 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All coagulation factor viii products

Authorised across Europe · EMA

The same active substance is authorised in 3 EEA countries. Names it is sold under:

  • Iceland · Nuwiq
  • Liechtenstein · Nuwiq
  • Norway · Nuwiq

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/cbef8c4c-0922-4e75-8f16-748a0582a6e1
GET /v1/drugs/cbef8c4c-0922-4e75-8f16-748a0582a6e1?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Poeder en oplosmiddel voor oplossing voor injectie",
  "route": "Intraveneus gebruik",
  "soort": null,
  "source": "cbg_meb",
  "smpc_url": "https://www.ema.europa.eu/en/documents/product-information/nuwiq-epar-product-information_nl.pdf",
  "strength": null,
  "atc_label": "Coagulation Factor VIII",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp121120",
  "excipients": [
    "ARGININEHYDROCHLORIDE, (L-)",
    "CALCIUMCHLORIDE 2-WATER (E 509)",
    "NATRIUMCHLORIDE",
    "POLOXAMEER 188",
    "SACCHAROSE",
    "TRINATRIUMCITRAAT 2-WATER (E 331)",
    "WATER VOOR INJECTIE"
  ],
  "substances": [
    "SIMOCTOCOG ALFA"
  ],
  "leaflet_url": null,
  "authorised_at": "2018/03/23",
  "procedure_number": "EMEA/H/C/002813",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "EU/1/14/936",
  "additional_monitoring": "N"
}
API referenceMCP serverPlans

See everything about coagulation factor viii.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console