United States· US:60505-6414_81a31a0f-1d41-16fb-02d1-418357788c6c
IVRA
A melphalan product containing melphalan hydrochloride, registered in United States by Apotex Corp. The same ATC class is registered in 17 of our 19 countries.
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
Where it is registered
Melphalan is registered in 17 of 19 countries.
Countries holding a registration under ATC L01AA03 (melphalan), each read from that country’s own register.
- This record: United States, from FDA National Drug Code directory (United States)
- 10 of them publish a price we can compare per daily dose
Melphalan · ATC L01AA03
17 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of melphalan costs, country by country.
Normalised to the WHO defined daily dose (2 mg), the median price runs from $0.79 in Italy to $3.83 in Switzerland — a ×4.8 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Melphalan · price per daily dose (2 mg)
USD · FX 28 Sept 2026
- CH Switzerland$3.83
- FR France$0.89
- IT Italy$0.79
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- MELPHALAN HYDROCHLORIDE
- Manufacturer
- Apotex Corp
- Country
- United States (US)
- ATC code
- L01AA03
- ATC class
- Melphalan
- Defined daily dose
- 2 mg, O
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 27, 2026
Packs & prices · 1
- ndc1160505-6414-1
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
242 interactions on record for melphalan.
Graded by severity as the source publishes them — 32 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Melphalan · interactions on record
242 records
- 32 severe
- 100 moderate
- 25 minor
- 85 info
Most severe, free to view
- Nalidixic acidJ01MB02severe
- ThiotepaL01AC01severe
- CladribineL01BB04severe
- Talimogene laherparepvecL01XL02severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Melphalan in 17 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomAlkeran 2mg tabletsAspen Pharma Trading Ltd
- GermanyAlkeranAspen Pharma Trading Limited
- NetherlandsAlkeran 2 mg, filmomhulde tablettenAspen Pharma Trading Limited
- SpainALKERAN 2 MG COMPRIMIDOS RECUBIERTOS CON PELICULAAspen Pharma Trading Limited
- FinlandAlkeranParanova Oy
- SwedenAlkeran 2 mg Filmdragerad tablettAspen Pharma Trading Limited
- FranceALKERAN 2 mg, comprimé pelliculéASPEN PHARMA TRADING (IRLANDE)
- SwitzerlandAlkeran
Authorised across Europe · EMA
The same active substance is authorised in 29 EEA countries. Names it is sold under:
- Austria · Alkeran, Melphalan Hikma
- Belgium · Alkeran, Melfalan Tillomed
- Cyprus · Melfalan Tillomed
- Czechia · Alkeran, Melphalan Zentiva
- Germany · Alkeran, Melphalan
- Denmark · Alkeran, Melphalan Macure
- Estonia · Alkeran
- Spain · Alkeran, Melfalán Aspen
- Finland · Alkeran, Melphalan Macure
- France · Alkeran, Melphalan Hikma
- United Kingdom (Northern Ireland) · Melphalan, Melphalan Accord-Uk
- Greece · Demephan, Melphalan Tillomed
- Croatia · Melfalan Pliva, Melfalan Tillomed
- Hungary · Melphalan Teva, Melphalan Zentiva
- Ireland · Alkeran, Melphalan Tillomed
- Iceland · Alkeran, Phelinun
- Italy · Alkeran, Melfalan Hikma
- Liechtenstein · Phelinun
- Lithuania · Alkeran, Melphalan Zentiva
- Luxembourg · Alkeran, Melphalan Aqvida
- Latvia · Alkeran, Melphalan Tillomed
- Netherlands · Alkeran, Melfalan Amarox
- Norway · Alkeran, Melphalan Macure
- Poland · Alkeran, Melphalan Zentiva
- Portugal · Alkeran, Melfalano Eugia
- Romania · Alkeran, Melfalan Teva
- Sweden · Alkeran, Melfalan Sun
- Slovenia · Alkeran, Melfalan Teva
- Slovakia · Alkeran, Melphalan Zentiva
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/caddac43-46e3-401b-b52e-1b5f2a6c311c GET /v1/drugs/caddac43-46e3-401b-b52e-1b5f2a6c311c?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"route": "INTRAVENOUS",
"source": "ndc",
"strength": "90",
"substance": "MELPHALAN HYDROCHLORIDE",
"productndc": "60505-6414",
"dosage_form": "INJECTION, SOLUTION",
"dea_schedule": null,
"strength_unit": "mg/mL",
"application_number": "NDA217110",
"marketing_category": "NDA"
}See everything about melphalan.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.