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Ireland· IE-PA-PA0208/005/001

Entonox

A nitrous oxide product containing oxygen + nitrous oxide, registered in Ireland by BOC Gases Ireland Ltd. The same ATC class is registered in 12 of our 19 countries.

ATC N01AX13

Checked against HPRA (Ireland) on

Informational only — not a medical device.

SOURCE REGISTER · IEHPRA (Ireland)normalisedEntonoxATCN01AX13REGISTER NO.IE-PA-PA0208/005/001PACKS LISTED1CHECKEDSeptember 28, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about oxygen + nitrous oxideAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Nitrous oxide is registered in 12 of 19 countries.

Countries holding a registration under ATC N01AX13 (nitrous oxide), each read from that country’s own register.

  • This record: Ireland, from HPRA (Ireland)
  • 8 of them publish a price we can compare per daily dose
Search nitrous oxide products by name

Nitrous oxide · ATC N01AX13

12 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

HPRA (Ireland)
Active substance
Oxygen + Nitrous oxide
Manufacturer
BOC Gases Ireland Ltd
Country
Ireland (IE)
ATC code
N01AX13
ATC class
Nitrous oxide
Reimbursed
Not published by this register
Source register
HPRA (Ireland)
Last checked
September 28, 2026

Packs & prices · 1

  • ie_pa_number
    PA0208/005/001

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

9 interactions on record for nitrous oxide.

Graded by severity as the source publishes them — 3 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check nitrous oxide against other medicinesHow interaction checks work

Nitrous oxide · interactions on record

9 records

  • 3 severe
  • 6 moderate

Most severe, free to view

  • MethotrexateL01BA01severe
  • MethotrexateL04AX03severe
  • MethotrexatM01CX01severe
  • OpiumA07DA02moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Nitrous oxide in 12 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All nitrous oxide products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

  • Austria · Donopa, Kalinox
  • Belgium · Actynox, Antafil
  • Bulgaria · Донопа
  • Cyprus · Entonox
  • Czechia · Actynox, Entonox
  • Germany · Donopa, Livopan
  • Denmark · Kalinox, Latox
  • Estonia · Entonox, Serynox 50%/50%
  • Spain · Actynox, Donopa
  • Finland · Livopan
  • France · Actynox, Antasol
  • United Kingdom (Northern Ireland) · Donopa, Entonox
  • Greece · Donopa, Entonox
  • Croatia · Donopa, Serynox 50%/50%
  • Hungary · Donopa, Livopan
  • Iceland · Latox, Livopan
  • Italy · Donopa, Kalinox
  • Lithuania · Entonox, Serynox 50%/50%
  • Luxembourg · Antafil, Kalinox
  • Latvia · Entonox, Serynox 50%/50%
  • Malta · Entonox
  • Netherlands · Actynox, Donopa
  • Norway · Livopan
  • Poland · Entonox, Serynox 50% + 50%
  • Portugal · Actynox, Kalinox
  • Romania · Entonox, Serynox 50% / 50%
  • Sweden · Kalinox, Latox
  • Slovenia · Donopa, Serynox 50%/50 %
  • Slovakia · Actynox, Entonox

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/cab7e5f4-3292-4354-8f14-e8e577495acd
GET /v1/drugs/cab7e5f4-3292-4354-8f14-e8e577495acd?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Medicinal gas, compressed",
  "routes": [
    "Inhalation use"
  ],
  "source": "hpra",
  "atc_all": [
    "N01AX",
    "N01AX13"
  ],
  "strength": null,
  "pa_number": "PA0208/005/001",
  "substances": [
    "Oxygen",
    "Nitrous oxide"
  ],
  "legal_basis": "Well-established use application (Article 10a of Directive No 2001/83/EC)",
  "market_info": "Marketed",
  "authorised_at": "01/04/1980",
  "dispensing_status": "Product subject to prescription which may not be renewed (A)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": null
}
API referenceMCP serverPlans

See everything about nitrous oxide.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console