Spain· ES:91313
DUABRIMA 2 MG/ML + 5 MG/ML COLIRIO EN SOLUCION
A medicinal product containing brimonidina + timolol, registered in Spain by Horus Pharma.
Checked against AEMPS CIMA (Spain) on
Informational only — not a medical device.
The record
At a glance
AEMPS CIMA (Spain)- Active substance
- brimonidina + timolol
- Manufacturer
- Horus Pharma
- Country
- Spain (ES)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- AEMPS CIMA (Spain)
- Last checked
- June 8, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Brimonidina + timolol in 13 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesBrimonidine tartrate and Timolol maleateNorthStar RxLLC
- United KingdomBrimonidine 2mg/ml / Timolol 5mg/ml eye dropsViatris UK Healthcare Ltd
- CzechiaBRIMONIDIN/TIMOLOL OLIKLAOlikla s.r.o., Kostelec nad Černými Lesy
- FranceBRIMONIDINE/TIMOLOL BIOGARAN 2 mg/mL + 5 mg/mL, collyre en solutionBIOGARAN
- GermanyBrimonidin/Timolol AlAliud Pharma Gmbh
- SwedenCombigan 2 mg/ml + 5 mg/ml Ögondroppar, lösningEbb Medical AB
- CanadaAPO-BRIMONIDINE-TIMOPAPOTEX INC
- NetherlandsBrimonidine/Timolol Blumont 2 mg/ml + 5 mg/ml oogdruppels, oplossingBlumont Ofta Trading Limited
Authorised across Europe · EMA
The same active substance is authorised in 27 EEA countries. Names it is sold under:
- Austria · Bazofex, Brimosine Duo
- Belgium · Combigan
- Bulgaria · Brimosine Duo, Бримонидин/Тимолол Ромфарм
- Cyprus · Brimonidine Tartrate / Timolol Kleva
- Czechia · Brimonidin/Timolol Olikla, Combigan
- Germany · Brimonidin/Timolol Pharmathen, Brimosine Duo
- Denmark · Brimonidin/Timolol Stada, Brimonidintartrat/Timolol Doc Generici
- Estonia · Combigan
- Finland · Combigan
- France · Brimonidine /Timolol Viatris, Brimonidine/Timolol Biogaran
- United Kingdom (Northern Ireland) · Abrivis Duo, Brimonidine Tartrate /Timolol Generics [uk]
- Greece · Brimontal-Co, Combigan
- Croatia · Bericomb, Combigan
- Hungary · Combigan
- Ireland · Combigan
- Italy · Brimocomb, Brimonidina E Timololo Mylan
- Lithuania · Combigan
- Luxembourg · Combigan
- Latvia · Combigan
- Netherlands · Brimonidinetartraat/Timolol Blumont, Combigan
- Norway · Combigan
- Poland · Combigan
- Portugal · Bericomb, Bglau Duo
- Romania · Briminodină/Timolol Rompharm, Combigan
- Sweden · Combigan
- Slovenia · Combigan
- Slovakia · Bericomb, Brimonidin/Timolol Olikla
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of AEMPS CIMA (Spain). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ca5cbb18-8e8e-4294-bef6-e623a35597fa GET /v1/drugs/ca5cbb18-8e8e-4294-bef6-e623a35597fa?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"cpresc": "Medicamento Sujeto A Prescripción Médica",
"estado": "{\"aut\":1780487164000}",
"nregistro": "91313",
"substance": "brimonidina + timolol"
}See everything about brimonidina + timolol.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.