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Switzerland· 41330001

Prothromplex NF 500 I.E., Pulver und Lösungsmittel zur Herstellung einer Injektionslösung

A coagulation factor ix, ii, vii and x in combination product containing factor ii coagulationis humanus, factor vii coagulationis humanus, factor ix coagulationis humanus, factor x coagulationis humanus, proteinum humanum c, registered in Switzerland by Takeda Pharma AG and dispensed under Swissmedic category B, on the national reimbursement list. The same ATC class is registered in 11 of our 19 countries.

Reimbursed in Switzerland (BAG SL)Cat B (Swissmedic)ATC B02BD01

Checked against Swissmedic (Switzerland) on

Informational only — not a medical device.

SOURCE REGISTER · CHSwissmedic (Switzerland)normalisedProthromplex NF 500 I.E., Pulver und …ATCB02BD01REGISTER NO.41330001PACKS LISTED1CHECKEDSeptember 12, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about factor ii coagulationis humanus, factor vii coagulationis humanus, factor ix coagulationis humanus, factor x coagulationis humanus, proteinum humanum cAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Coagulation factor ix, ii, vii and x in combination is registered in 11 of 19 countries.

Countries holding a registration under ATC B02BD01 (coagulation factor ix, ii, vii and x in combination), each read from that country’s own register.

  • This record: Switzerland, from Swissmedic (Switzerland)
  • 7 of them publish a price we can compare per daily dose
Search coagulation factor ix, ii, vii and x in combination products by name

Coagulation factor ix, ii, vii and x in combination · ATC B02BD01

11 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

Swissmedic (Switzerland)
Active substance
factor II coagulationis humanus, factor VII coagulationis humanus, factor IX coagulationis humanus, factor X coagulationis humanus, proteinum humanum C
Manufacturer
Takeda Pharma AG
Country
Switzerland (CH)
ATC code
B02BD01
ATC class
Coagulation factor IX, II, VII and X in combination
Defined daily dose
1.6 TSD, E
Swissmedic category
B
Reimbursed
Yes
Source register
Swissmedic (Switzerland)
Last checked
September 12, 2026

Packs & prices · 1

1 priced
  • gtin
    7680413300015
    Durchstf 17 ml
    CHF 315.4

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

3 interactions on record for coagulation factor ix, ii, vii and x in combination.

Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check coagulation factor ix, ii, vii and x in combination against other medicinesHow interaction checks work

Coagulation factor ix, ii, vii and x in combination · interactions on record

3 records

  • 2 severe
  • 1 moderate

Most severe, free to view

  • CarfilzomibL01XG02severe
  • CarfilzomibL01XX45severe
  • PegvaliaseA16AB19moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same class

Other records under B02BD01

Coagulation factor ix, ii, vii and x in combination, as other registers publish it.

All coagulation factor ix, ii, vii and x in combination products

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Swissmedic (Switzerland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/c95fc934-a479-4352-a2d9-bd707c8ce59e
GET /v1/drugs/c95fc934-a479-4352-a2d9-bd707c8ce59e?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "unit": null,
  "strength": "proteinum 250-625 mg + factor ii coagulationis humanus (prothrombinum) 500 UI + factor vii coagulationis humanus 417 UI + factor ix coagulationis humanus 500 UI + factor x coagulationis humanus 500 UI + proteinum c humanum 333 UI",
  "valid_from": "2024-10-01",
  "limitations": null,
  "galenic_form": "Trockensub 500 IE c Solv",
  "therapeutic_area": null,
  "sl_inclusion_date": "2024-10-01",
  "self_retention_pct": 10
}
API referenceMCP serverPlans

See everything about coagulation factor ix, ii, vii and x in combination.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console