Netherlands· NL-10e619798702

Vagirux 10 microgram tabletten voor vaginaal gebruik

A estradiol product containing estradiol 0,5-water, registered in Netherlands by Gedeon Richter Plc. The same ATC class is registered in 13 of our 19 countries.

ATC G03CA03

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about estradiol 0,5-waterAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Estradiol is registered in 13 of 19 countries.

Countries holding a registration under ATC G03CA03 (estradiol), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
9 of them publish a price we can compare per daily dose

Search estradiol products by name

Estradiol · ATC G03CA03

13 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of estradiol costs, country by country.

Normalised to the WHO defined daily dose (0.3 mg), so markets compare like for like.

1 market with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Estradiol · price per daily dose (0.3 mg)

USD · FX 28 Sept 2026

CH Switzerland$0.11

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: ESTRADIOL 0,5-WATER
Manufacturer: Gedeon Richter Plc
Country: Netherlands (NL)
ATC code: G03CA03
ATC class: Estradiol
Defined daily dose: 0.3 mg, N
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
124964

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

328 interactions on record for estradiol.

Graded by severity as the source publishes them — 7 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check estradiol against other medicines How interaction checks work

Estradiol · interactions on record

328 records

7 severe
177 moderate
3 minor
131 info

Most severe, free to view

Tranexamic acidB02AA02severe
HeminB06AB01severe
CarfilzomibL01XG02severe
CarfilzomibL01XX45severe

10 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Estradiol in 17 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All estradiol products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Estrofem, Femseven
Belgium · Estradiol Besins, Estrofem
Bulgaria · Естрогел, Естрофем
Cyprus · Vagifem
Czechia · Estradiol Besins, Estrofem
Germany · Estradiol Fem Jenapharm, Estrifam
Denmark · Divigel, Ercostrol
Estonia · Divigel, Estradiol Besins
Spain · Divigel, Estradiol Besins
Finland · Divigel, Estradot
France · Dermestril, Dermestril Septem
United Kingdom (Northern Ireland) · Elleste, Elleste Solo Mx
Greece · Vagifem
Croatia · Estradiol Besins, Estrofem
Hungary · Estradiol Besins, Estrofem
Ireland · Divigel, Estradiol Sun
Iceland · Estring, Estrofem
Italy · Dermestril, Femseven
Lithuania · Divigel, Estradiol Besins
Luxembourg · Dermestril 100, Dermestril 25
Latvia · Estradiol Besins, Estrofem
Malta · Oestrogel Pump-Pack, Vagifem
Norway · Estradot, Estrogel
Poland · Divigel, Estrofem
Portugal · Dermestril, Estradot
Romania · Estradiol Besins
Sweden · Divigel, Estradiol Besins
Slovenia · Estradiol Besins, Vagifem
Slovakia · Estradiol Besins, Estrofem

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/c8875bc8-523a-4e5d-b3ac-f1e8ef0cbada
GET /v1/drugs/c8875bc8-523a-4e5d-b3ac-f1e8ef0cbada?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Tablet voor vaginaal gebruik",
  "route": "Vaginaal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h124964_smpc.pdf",
  "strength": null,
  "atc_label": "Estradiol",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg124964",
  "excipients": [
    "HYPROMELLOSE (E 464)",
    "LACTOSE 1-WATER",
    "MACROGOL",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MAÏSZETMEEL"
  ],
  "substances": [
    "ESTRADIOL 0,5-WATER"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h124964.pdf",
  "authorised_at": "2020/10/29",
  "procedure_number": "HU/H/0633/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "124964",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about estradiol.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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