Netherlands· NL-ecdb38ae4f70

Distikstofoxide medicinaal SOL, medicinaal gas, vloeibaar gemaakt 100% v/v

A nitrous oxide product containing distikstofoxide (e 942), registered in Netherlands by SOL SpA. The same ATC class is registered in 12 of our 19 countries.

ATC N01AX13

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about distikstofoxide (e 942)Answers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Nitrous oxide is registered in 12 of 19 countries.

Countries holding a registration under ATC N01AX13 (nitrous oxide), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
8 of them publish a price we can compare per daily dose

Search nitrous oxide products by name

Nitrous oxide · ATC N01AX13

12 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)

Active substance: DISTIKSTOFOXIDE (E 942)
Manufacturer: SOL SpA
Country: Netherlands (NL)
ATC code: N01AX13
ATC class: Nitrous oxide
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
32961

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

9 interactions on record for nitrous oxide.

Graded by severity as the source publishes them — 3 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check nitrous oxide against other medicines How interaction checks work

Nitrous oxide · interactions on record

9 records

3 severe
6 moderate

Most severe, free to view

MethotrexateL01BA01severe
MethotrexateL04AX03severe
MethotrexatM01CX01severe
OpiumA07DA02moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Nitrous oxide in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All nitrous oxide products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Distickstoffmonoxid Westfalen, Stickoxydul Medizinisch
Belgium · Dinitrox, Distickstoff Oxid Air Products
Bulgaria · Nitrous Oxide Messer 100%, Медицински Диазотен Оксид Sol
Cyprus · Medicinal Nitrous Oxide Linde- Hadjikyriakos Gas Ltd
Czechia · Medicinální Oxid Dusný, Medicinální Oxid Dusný Messer
Germany · Distickstoffmonoxid Air Products, Distickstoffmonoxid Für Medizinische Zwecke Nippon Gases Deutschland
Denmark · Medicinsk Dinitrogenoxid Air Liquide, Medicinsk Dinitrogenoxid Nippon Gases Scandinavia
Estonia · Dilämmastikoksiid, Niontix
Spain · Óxido Nitroso, Oxido Nitroso Medicinal Air Liquide
Finland · Lääkkeellinen Ilokaasu Awo, Niontix
France · Protoxyde D'azote Medicinal, Protoxyde D'azote Medicinal Air Liquide Sante France
United Kingdom (Northern Ireland) · Medical Nitrous Oxide Boc, Nitrous Oxide
Greece · Niontix, Φαρμακευτικό Πρωτοξείδιο Του Αζώτου Sol
Croatia · Dušični Oksidul Utp, Dušikov(I) Oksid Messer
Hungary · Dinitrogén-Oxid Air Products, Dinitrogén-Oxid Bus-Oxy
Ireland · Medical Nitrous Oxide Boc Gases Ireland, Nitrous Oxide Medicinal Sol
Iceland · Lyfjatvíköfnunarefnisoxíð Strandmøllen, Niontix
Italy · Alfaprot, Azoto Protossido Air Liquide Sanità
Lithuania · Diazoto Oksidas Elme Messer Gaas, Diazoto Oksidas Gaschema
Luxembourg · Niontix, Protoxyde D'azote Médical Air Liquide Santé International
Latvia · Mediciniskais Slapekla Oksiduls, Saskidrinatais, Niontix
Malta · Medical Nitrous Oxide Boc Gases Ireland
Norway · Medisinsk Lystgass, Medisinsk Lystgass Nippon Gases Scandinavia
Poland · Podtlenek Azotu, Podtlenek Azotu Air Products
Portugal · Niontix, Protóxido De Azoto
Romania · Niontix, Protoxid De Azot Medicinal Siad
Sweden · Medicinsk Lustgas Air Liquide, Medicinsk Lustgas Nippon Gases Scandinavia
Slovenia · Medicinski Didušikov Oksid Istrabenz Plini, Medicinski Didusikov Oksid Messer
Slovakia · Medicinálny Oxid Dusný Siad, Medicinálny Oxid Dusný Sol

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/c7a9cacc-d72a-484f-aa7b-b9f748c66038
GET /v1/drugs/c7a9cacc-d72a-484f-aa7b-b9f748c66038?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Medicinaal gas, vloeibaar gemaakt",
  "route": "Inhalatie",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h32961_smpc.pdf",
  "strength": null,
  "atc_label": "Nitrous Oxide",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg32961",
  "excipients": [
    "GEEN HULPSTOFFEN"
  ],
  "substances": [
    "DISTIKSTOFOXIDE (E 942)"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h32961.pdf",
  "authorised_at": "2009/07/31",
  "procedure_number": "NL/H/2783/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "32961",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about nitrous oxide.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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