Ireland· IE-PA-PPA0465/109/002

Cozaar Comp 100 mg/25 mg film-coated tablets

A losartan product containing losartan potassium + hydrochlorothiazide, registered in Ireland by PCO Manufacturing Ltd.. The same ATC class is registered in 19 of our 19 countries.

ATC C09CA01

Checked against HPRA (Ireland) on September 28, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about losartan potassium + hydrochlorothiazideAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Losartan is registered in 19 of 19 countries.

Countries holding a registration under ATC C09CA01 (losartan), each read from that country’s own register.

This record: Ireland, from HPRA (Ireland)
11 of them publish a price we can compare per daily dose

Search losartan products by name

Losartan · ATC C09CA01

19 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Japan
Netherlands
Norwayprice
Polandprice
Spainprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of losartan costs, country by country.

Normalised to the WHO defined daily dose (50 mg), the median price runs from $0.033 in United States to $0.61 in Switzerland — a ×19 gap.

5 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown
US figures are pharmacy acquisition cost (CMS NADAC), not retail

Open the full comparison — free account Drug prices for market access

Losartan · price per daily dose (50 mg)

USD · FX 28 Sept 2026

CH Switzerland$0.61
IT Italy$0.30
ES Spain$0.17
FR France$0.10
US United States$0.033 (acquisition cost)

Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

HPRA (Ireland)

Active substance: Losartan potassium + Hydrochlorothiazide
Manufacturer: PCO Manufacturing Ltd.
Country: Ireland (IE)
ATC code: C09CA01
ATC class: Losartan
Defined daily dose: 50 mg, O
Reimbursed: Not published by this register
Source register: HPRA (Ireland)
Last checked: September 28, 2026

Packs & prices · 1

ie_pa_number
PPA0465/109/002

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

431 interactions on record for losartan.

Graded by severity as the source publishes them — 7 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check losartan against other medicines How interaction checks work

Losartan · interactions on record

431 records

7 severe
139 moderate
2 minor
198 info

Most severe, free to view

Potassium chlorideA12BA01severe
Potassium citrateA12BA02severe
Potassium gluconateA12BA05severe
Potassium chlorideB05XA01severe

85 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Losartan in 14 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All losartan products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Cosaar, Losarcomp
Belgium · Co-Losartan, Co-Losartan Teva
Bulgaria · Ко-Хипертоник, Лозап H
Cyprus · Losar Plus, Losartan/Hydrochlorothiazide Krka
Czechia · Lorista H, Losartan/Hydrochlorothiazide Zentiva
Germany · Fortzaar, Lorzaar Plus
Denmark · Ancozan Comp, Cozaar Comp.
Estonia · Lorista H, Lorista H 100/25 Mg
Spain · Cozaar Plus, Fortzaar
Finland · Cozaar Comp, Cozaar Comp Forte
France · Fortzaar, Hyzaar
United Kingdom (Northern Ireland) · Cozaar Comp, Losartan Potassium / Hydrochlorothiazide Generics (Uk)
Greece · Co-Rabolan, Faxiven
Croatia · Fortzaar, Hyzaar
Hungary · Co-Arbartan, Hyzaar
Iceland · Cozaar Comp, Cozaar Comp Forte
Italy · Forzaar, Hizaar
Lithuania · Lorista H, Lozap H
Luxembourg · Cozaar Plus, Cozaar Plus Forte
Latvia · Lorista H
Malta · Losartan/Hydrochlorothiazide Aurobindo
Netherlands · Cozaar Plus, Entrizen/Hct
Norway · Asolzid, Cozaar Comp
Poland · Hyzaar, Hyzaar Forte
Portugal · Cotiasar, Cozaar Plus
Romania · Lorista H, Lorista Hl
Sweden · Cozaar Comp, Cozaar Comp Forte
Slovenia · Lorista H, Lorista Hd
Slovakia · Lorista H, Losartan/Hydrochlorothiazid Stada

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/c70127df-65c1-4e5d-ae54-34e647841567
GET /v1/drugs/c70127df-65c1-4e5d-ae54-34e647841567?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Film-coated tablet",
  "routes": [
    "Oral use"
  ],
  "source": "hpra",
  "atc_all": [
    "C09CA",
    "C09CA01"
  ],
  "strength": null,
  "pa_number": "PPA0465/109/002",
  "substances": [
    "Losartan potassium",
    "Hydrochlorothiazide"
  ],
  "legal_basis": "Parallel importation notified in accordance with Article 76(3) of Directive 2001/83/EC",
  "market_info": "Unknown",
  "authorised_at": "08/02/2008",
  "dispensing_status": "Product subject to prescription which may be renewed (B)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": "IC0031-027-003"
}

API reference MCP server Plans

See everything about losartan.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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