Symtuza

{
  "unii": {
    "unii": "LW2E03M5PG",
    "rxcui": "1306284",
    "inchikey": "ZCIGNRJZKPOIKD-CQXVEOKZSA-N",
    "display_name": "COBICISTAT",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "ORAL",
  "spl_meta": {
    "85a17d00-6b7c-41ea-a6b3-5ad924820dab": {
      "match": "brand_token",
      "title": "SYMTUZA (DARUNAVIR, COBICISTAT, EMTRICITABINE, AND TENOFOVIR ALAFENAMIDE) TABLET, FILM COATED [JANSSEN PRODUCTS LP]",
      "spl_version": "23",
      "published_date": "2026-04-20"
    }
  },
  "productid": "59676-800_a8468da1-a6e7-4a14-a108-23915ccaeee8",
  "productndc": "59676-800",
  "dosage_form": "TABLET, FILM COATED",
  "orange_book": {
    "appl_no": "210455",
    "products": [
      {
        "rs": true,
        "rld": true,
        "te_code": null,
        "strength": "150MG;800MG;200MG;EQ 10MG BASE",
        "product_no": "001",
        "approval_date": "Jul 17, 2018"
      }
    ],
    "appl_type": "N"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "COBICISTAT; DARUNAVIR; EMTRICITABINE; TENOFOVIR ALAFENAMIDE",
  "proprietary_name": "Symtuza",
  "active_ingred_unit": "mg/1; mg/1; mg/1; mg/1",
  "application_number": "NDA210455",
  "marketing_category": "NDA",
  "nonproprietary_name": "Darunavir, Cobicistat, Emtricitabine, and Tenofovir alafenamide",
  "start_marketing_date": "20180717",
  "active_numerator_strength": "150; 800; 200; 10"
}