United States· US:41520-711_30b1a215-edf0-47f0-a297-5ac78cced330
careone nicotine
A nicotine product containing nicotine polacrilex, registered in United States by American Sales Company. The same ATC class is registered in 15 of our 19 countries.
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
Where it is registered
Nicotine is registered in 15 of 19 countries.
Countries holding a registration under ATC N07BA01 (nicotine), each read from that country’s own register.
- This record: United States, from FDA National Drug Code directory (United States)
- 9 of them publish a price we can compare per daily dose
Nicotine · ATC N07BA01
15 / 19 countries
- Belgiumprice
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of nicotine costs, country by country.
Normalised to the WHO defined daily dose (60 mg), the median price runs from $4.40 in France to $6.98 in United States — a ×1.6 gap.
- United States: $6.98 per daily dose (median across products in the class)
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Nicotine · price per daily dose (60 mg)
USD · FX 28 Sept 2026
- US United States$6.98 (acquisition cost)
- FR France$4.40
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- Nicotine polacrilex
- Manufacturer
- American Sales Company
- Country
- United States (US)
- ATC code
- N07BA01
- ATC class
- Nicotine
- Defined daily dose
- 60 mg, Inhalation
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 12, 2026
Packs & prices · 2
- ndc11415207116020 BLISTER PACK in 1 CARTON (41520-711-60) / 1 GUM, CHEWING in 1 BLISTER PACK
- ndc114152071178100 BLISTER PACK in 1 CARTON (41520-711-78) / 1 GUM, CHEWING in 1 BLISTER PACK
Regulatory notes
Interactions
129 interactions on record for nicotine.
Graded by severity as the source publishes them — 6 moderate. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Nicotine · interactions on record
129 records
- 6 moderate
- 5 minor
- 118 info
Most severe, free to view
- CeritinibL01ED02moderate
- AlpelisibL01EM03moderate
- CeritinibL01XE28moderate
- AlpelisibL01XX65moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Nicotine in 14 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- IrelandNicorette Freshfruit 2mg Medicated Chewing GumJNTL Consumer Health I (Ireland) Limited
- SwedenNikoral Frukt 2 mg Medicinskt tuggummiAlkalon A/S
- United KingdomBoots NicAssist 10mg InhalatorThe Boots Company Plc
- CzechiaNICORETTE CLASSIC GUMMcNeil AB, Helsingborg
- FinlandExmoActavis Group PTC ehf
- BelgiumNicopatch 14 mg/24 hPierre Fabre Médicament
- PolandNicorama FruitmintEnorama Pharma AB
- NetherlandsCuralyn Nicotine kauwgom mint 2 mg suikervrijMAE Holding B.V.
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Niconex, Nicorette
- Belgium · Nicorette, Nicorette Freshmint
- Bulgaria · Никорет Айсминт, Никорет Бериминт
- Cyprus · Nicorette, Nicorette Clear Patch
- Czechia · Nicorette Classic Gum, Nicorette Freshfruit Gum
- Germany · Mit Minzgeschmack, Mit Zitronengeschmack
- Denmark · Nicolex, Nicorette
- Estonia · Nicorette Coolberry, Nicorette Coolmint
- Spain · Nicorette, Nicorette Bucomist
- Finland · Nicorette, Nicorette Berrymint
- France · Nicopass Menthe Fraicheur Sans Sucre, Édulcorée À L'aspartam Et À L’acésulfame Potassique, Nicopass Reglisse Menthe Sans Sucre, Édulcorée À L'aspartam Et À L'acésulfame Potassique
- United Kingdom (Northern Ireland) · Asda Replace, Boots Nicassist
- Greece · Nicorette, Nicorette Clear Patch
- Croatia · Nicorette, Nicorette Freshfruit
- Hungary · Nicorette Berrymint, Nicorette Freshfruit Gum
- Ireland · Nicorette, Nicorette Cools
- Iceland · Nicorette, Nicorette Classic
- Italy · Nicorette, Nicorette Gusto Menta Forte
- Lithuania · Nicorette Coolmint, Nicorette Freshfruit
- Luxembourg · Nicorette, Nicorette Freshmint
- Latvia · Nicorette Coolberry, Nicorette Coolmint
- Malta · Nicorette, Nicorette Freshmint
- Netherlands · Nicorette Freshmint, Nicorette Fruit
- Norway · Nicorette, Nicorette Med Nøytral Smak
- Poland · Nicorama Fruitmint, Nicorama Mint
- Portugal · Nicontrol Menta, Nicopatch Tts
- Romania · Nicorette Berrymint, Nicorette Clear
- Sweden · Nicorama Fruktmint, Nicorama Mint
- Slovenia · Nicorette, Nicorette Freshfruit Z Okusom Sadja
- Slovakia · Nicorette Classic Gum, Nicorette Freshfruit Gum
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/c3bf5cf8-5125-401c-a015-57901b07c450 GET /v1/drugs/c3bf5cf8-5125-401c-a015-57901b07c450?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"unii": {
"unii": "6M3C89ZY6R",
"rxcui": "7407",
"inchikey": "SNICXCGAKADSCV-JTQLQIEISA-N",
"display_name": "NICOTINE",
"substance_type": "chemical",
"ingredient_type": "INGREDIENT SUBSTANCE"
},
"route": "ORAL",
"livertox": {
"summary": null,
"livertox_id": null,
"hepatotoxicity_score": 5
},
"spl_meta": {
"206f5483-7de1-4bc3-af27-190e211bcb95": {
"match": "brand_token",
"title": "CAREONE ACID RELIEF (FAMOTIDINE) TABLET, FILM COATED [AMERICAN SALES COMPANY]",
"spl_version": "9",
"published_date": "2026-05-25"
}
},
"productid": "41520-711_30b1a215-edf0-47f0-a297-5ac78cced330",
"productndc": "41520-711",
"dosage_form": "GUM, CHEWING",
"orange_book": {
"appl_no": "206394",
"products": [
{
"rs": false,
"rld": false,
"te_code": null,
"strength": "EQ 2MG BASE",
"product_no": "001",
"approval_date": "Dec 15, 2016"
}
],
"appl_type": "A"
},
"dea_schedule": null,
"product_type": "HUMAN OTC DRUG",
"substance_name": "NICOTINE",
"proprietary_name": "careone nicotine",
"active_ingred_unit": "mg/1",
"application_number": "ANDA206394",
"marketing_category": "ANDA",
"nonproprietary_name": "Nicotine polacrilex",
"start_marketing_date": "20171113",
"active_numerator_strength": "2"
}See everything about nicotine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.