Belgium· BE-AMP-SAM157805-00
Spidifen 400 mg
A ibuprofen product containing ibuprofen arginine, registered in Belgium by Zambon. The same ATC class is registered in 12 of our 19 countries.
Checked against FAMHP / AFMPS (Belgium) on
Informational only — not a medical device.
Where it is registered
Ibuprofen is registered in 12 of 19 countries.
Countries holding a registration under ATC M01AE01 (ibuprofen), each read from that country’s own register.
- This record: Belgium, from FAMHP / AFMPS (Belgium)
- 8 of them publish a price we can compare per daily dose
Ibuprofen · ATC M01AE01
12 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
Price per daily dose
What a daily dose of ibuprofen costs, country by country.
Normalised to the WHO defined daily dose (1.2 g), the median price runs from $0.28 in Italy to $1.24 in Switzerland — a ×4.4 gap.
- 2 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Ibuprofen · price per daily dose (1.2 g)
USD · FX 28 Sept 2026
- CH Switzerland$1.24
- IT Italy$0.28
The record
At a glance
FAMHP / AFMPS (Belgium)- Active substance
- Ibuprofen Arginine
- Manufacturer
- Zambon
- Country
- Belgium (BE)
- ATC code
- M01AE01
- ATC class
- Ibuprofen
- Defined daily dose
- 1.2 g, O
- Reimbursed
- Not published by this register
- Source register
- FAMHP / AFMPS (Belgium)
- Last checked
- September 26, 2026
Packs & prices · 2
- be_apb1281492
- be_apb0745026
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
886 interactions on record for ibuprofen.
Graded by severity as the source publishes them — 71 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Ibuprofen · interactions on record
886 records
- 71 severe
- 306 moderate
- 15 minor
- 413 info
Most severe, free to view
- DicoumarolB01AA01severe
- WarfarinB01AA03severe
- DalteparinB01AB04severe
- EnoxaparinB01AB05severe
81 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Ibuprofen in 1 other country
What each register calls a product with the same active substance — salts and hydrates count as the same.
Authorised across Europe · EMA
The same active substance is authorised in 3 EEA countries. Names it is sold under:
- Spain · Difenadol Rapid, Espididol
- Hungary · Novorufen Rapid
- Portugal · Spidifen, Spidifen Aroma Cola-Limão
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FAMHP / AFMPS (Belgium). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/c3876c7c-a40c-4694-8281-8a7d7de5bd9b GET /v1/drugs/c3876c7c-a40c-4694-8281-8a7d7de5bd9b?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Granules for oral solution",
"source": "afmps",
"status": "AUTHORIZED",
"name_en": "Spidifen 400 mg",
"name_fr": "Spidifen 400 mg",
"name_nl": "Spidifen 400 mg",
"amp_code": "SAM157805-00",
"strengths": [
"400.0000",
"20.0000",
"200.0000",
"1835.0000",
"25.0000"
],
"pack_count": 1,
"substances": [
"Ibuprofen Arginine",
"Ibuprofen",
"Saccharin Sodium",
"Sodium Hydrogen Carbonate",
"Sucrose",
"Aspartame"
],
"medicine_type": "ALLOPATHIC",
"atc_description": "Ibuprofen",
"authorisation_numbers": [
"BE157805"
]
}See everything about ibuprofen.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.