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United States· US:50090-6857_fe4ca567-85b0-4385-8a6a-ac3499990236

Metformin Hydrochloride

A metformin product containing metformin hydrochloride, registered in United States by A-S Medication Solutions. The same ATC class is registered in 19 of our 19 countries.

ATC A10BA02Orange BookUS label

Checked against FDA National Drug Code directory (United States) on

Informational only — not a medical device.

SOURCE REGISTER · USFDA National Drug Code directory (Unite…normalisedMetformin HydrochlorideATCA10BA02REGISTER NO.US:50090-6857_fe4ca56…PACKS LISTED1CHECKEDSeptember 12, 2026

Where it is registered

Metformin is registered in 19 of 19 countries.

Countries holding a registration under ATC A10BA02 (metformin), each read from that country’s own register.

  • This record: United States, from FDA National Drug Code directory (United States)
  • 11 of them publish a price we can compare per daily dose

Metformin · ATC A10BA02

19 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Franceprice
  • Germany
  • Icelandprice
  • Ireland
  • Italyprice
  • Japan
  • Netherlands
  • Norwayprice
  • Polandprice
  • Spainprice
  • Sweden
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of metformin costs, country by country.

Normalised to the WHO defined daily dose (2 g), the median price runs from $0.10 in Spain to $0.52 in Switzerland — a ×5.0 gap.

  • United States: $0.11 per daily dose (median across products in the class)
  • Public list prices, converted to USD at the rate date shown
  • US figures are pharmacy acquisition cost (CMS NADAC), not retail

Metformin · price per daily dose (2 g)

USD · FX 28 Sept 2026

  • CH Switzerland$0.52
  • CZ Czechia$0.24
  • IT Italy$0.19
  • FR France$0.17
  • US United States$0.11 (acquisition cost)
  • ES Spain$0.10
Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)
Active substance
Metformin Hydrochloride
Manufacturer
A-S Medication Solutions
Country
United States (US)
ATC code
A10BA02
ATC class
Metformin
Defined daily dose
2 g, O
Reimbursed
Not published by this register
Source register
FDA National Drug Code directory (United States)
Last checked
September 12, 2026

Packs & prices · 1

  • ndc11
    5009068570
    90 TABLET, FILM COATED in 1 BOTTLE (50090-6857-0)

Regulatory notes

UNII (FDA substance ID)
786Z46389E
METFORMIN HYDROCHLORIDE
RxCUI 235743
Orange Book
A209882
ABABAB
DailyMed SPL labels
1 version tracked

Interactions

790 interactions on record for metformin.

Graded by severity as the source publishes them — 17 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Metformin · interactions on record

790 records

  • 17 severe
  • 353 moderate
  • 45 minor
  • 370 info

Most severe, free to view

  • EthanolB05XX04severe
  • IoxilanV08AB12severe
  • CimetidineA02BA01moderate
  • RanitidineA02BA02moderate

5 more interactions with mechanism and management, from a commercially licensed source.

Sign in to check
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Metformin in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All metformin products

Authorised across Europe · EMA

The same active substance is authorised in 30 EEA countries. Names it is sold under:

  • Austria · Diabetex, Glucophage
  • Belgium · Metformax, Metformin Activase 1000 Mg
  • Bulgaria · Meglucon Xr, Metformin Interdos Pharma
  • Cyprus · Brotmin, Glucophage
  • Czechia · Brotmin, Glucomet
  • Germany · Glucophage, Juformin
  • Denmark · Forminet, Lyomet
  • Estonia · Brotmin, Diabufor Xr
  • Spain · Brotmin, Dianben
  • Finland · Forminet, Glucophage
  • France · Glimezit, Glucophage
  • United Kingdom (Northern Ireland) · Abiano, Axpinet
  • Greece · Glucoformin, Glucofree
  • Croatia · Aglurab, Belformin
  • Hungary · Adimet, Adimet Xr
  • Ireland · Glucophage, Metformin Accord
  • Iceland · Forminet, Glucophage
  • Italy · Glucophage, Glucophage Unidie
  • Lithuania · Brotmin, Metfogamma
  • Luxembourg · Glucophage, Metformax
  • Latvia · Brotmin, Glucient Sr
  • Malta · Brotmin, Glyformin
  • Netherlands · Glucient Sr, Glycofren
  • Norway · Forminet, Glucophage
  • Poland · Abmetfina Xr, Avamina
  • Portugal · Allmet, Glucophage
  • Romania · Brotmin, Glucophage
  • Sweden · Forminet, Glucophage
  • Slovenia · Aglurab, Glucophage
  • Slovakia · Glucophage, Glucophage Xr

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/c2eedf6a-9bde-46a5-b2c7-1389d08ea8ff
GET /v1/drugs/c2eedf6a-9bde-46a5-b2c7-1389d08ea8ff?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "unii": {
    "unii": "786Z46389E",
    "rxcui": "235743",
    "inchikey": "OETHQSJEHLVLGH-UHFFFAOYSA-N",
    "display_name": "METFORMIN HYDROCHLORIDE",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "ORAL",
  "livertox": {
    "summary": null,
    "livertox_id": null,
    "hepatotoxicity_score": 2
  },
  "spl_meta": {
    "1cb2b2be-595c-4e72-8d2c-c1edc7f85682": {
      "match": "brand_token",
      "title": "METFORMIN HYDROCHLORIDE TABLET, FILM COATED, EXTENDED RELEASE [GOLDEN STATE MEDICAL SUPPLY, INC.]",
      "spl_version": "9",
      "published_date": "2026-06-01"
    }
  },
  "productid": "50090-6857_fe4ca567-85b0-4385-8a6a-ac3499990236",
  "productndc": "50090-6857",
  "dosage_form": "TABLET, FILM COATED",
  "orange_book": {
    "appl_no": "209882",
    "products": [
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "500MG",
        "product_no": "001",
        "approval_date": "Aug 27, 2018"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "850MG",
        "product_no": "002",
        "approval_date": "Aug 27, 2018"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "1GM",
        "product_no": "003",
        "approval_date": "Aug 27, 2018"
      }
    ],
    "appl_type": "A"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "METFORMIN HYDROCHLORIDE",
  "proprietary_name": "Metformin Hydrochloride",
  "active_ingred_unit": "mg/1",
  "application_number": "ANDA209882",
  "marketing_category": "ANDA",
  "nonproprietary_name": "Metformin Hydrochloride",
  "start_marketing_date": "20210517",
  "active_numerator_strength": "1000"
}

See everything about metformin.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.