United States· US:50090-6857_fe4ca567-85b0-4385-8a6a-ac3499990236
Metformin Hydrochloride
A metformin product containing metformin hydrochloride, registered in United States by A-S Medication Solutions. The same ATC class is registered in 19 of our 19 countries.
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
Where it is registered
Metformin is registered in 19 of 19 countries.
Countries holding a registration under ATC A10BA02 (metformin), each read from that country’s own register.
- This record: United States, from FDA National Drug Code directory (United States)
- 11 of them publish a price we can compare per daily dose
Metformin · ATC A10BA02
19 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Spainprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of metformin costs, country by country.
Normalised to the WHO defined daily dose (2 g), the median price runs from $0.10 in Spain to $0.52 in Switzerland — a ×5.0 gap.
- United States: $0.11 per daily dose (median across products in the class)
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Metformin · price per daily dose (2 g)
USD · FX 28 Sept 2026
- CH Switzerland$0.52
- CZ Czechia$0.24
- IT Italy$0.19
- FR France$0.17
- US United States$0.11 (acquisition cost)
- ES Spain$0.10
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- Metformin Hydrochloride
- Manufacturer
- A-S Medication Solutions
- Country
- United States (US)
- ATC code
- A10BA02
- ATC class
- Metformin
- Defined daily dose
- 2 g, O
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 12, 2026
Packs & prices · 1
- ndc11500906857090 TABLET, FILM COATED in 1 BOTTLE (50090-6857-0)
Regulatory notes
Interactions
790 interactions on record for metformin.
Graded by severity as the source publishes them — 17 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Metformin · interactions on record
790 records
- 17 severe
- 353 moderate
- 45 minor
- 370 info
Most severe, free to view
- EthanolB05XX04severe
- IoxilanV08AB12severe
- CimetidineA02BA01moderate
- RanitidineA02BA02moderate
5 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Metformin in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaBROTMINMedochemie Ltd., Limassol
- FinlandForminetSTADA Arzneimittel AG
- PolandAvaminaBioton S.A.
- FranceGLUCOPHAGE 1000 mg, comprimé pelliculé sécableDIFARMED (ESPAGNE)
- SwitzerlandGlucophage 1000
- SwedenForminet 1000 mg Filmdragerad tablettSTADA Arzneimittel AG
- SpainBROTMIN 1000 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFGMedochemie Iberia S.A.
- ItalyMETFONORMABIOGEN PHARMA S.P.A.
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Diabetex, Glucophage
- Belgium · Metformax, Metformin Activase 1000 Mg
- Bulgaria · Meglucon Xr, Metformin Interdos Pharma
- Cyprus · Brotmin, Glucophage
- Czechia · Brotmin, Glucomet
- Germany · Glucophage, Juformin
- Denmark · Forminet, Lyomet
- Estonia · Brotmin, Diabufor Xr
- Spain · Brotmin, Dianben
- Finland · Forminet, Glucophage
- France · Glimezit, Glucophage
- United Kingdom (Northern Ireland) · Abiano, Axpinet
- Greece · Glucoformin, Glucofree
- Croatia · Aglurab, Belformin
- Hungary · Adimet, Adimet Xr
- Ireland · Glucophage, Metformin Accord
- Iceland · Forminet, Glucophage
- Italy · Glucophage, Glucophage Unidie
- Lithuania · Brotmin, Metfogamma
- Luxembourg · Glucophage, Metformax
- Latvia · Brotmin, Glucient Sr
- Malta · Brotmin, Glyformin
- Netherlands · Glucient Sr, Glycofren
- Norway · Forminet, Glucophage
- Poland · Abmetfina Xr, Avamina
- Portugal · Allmet, Glucophage
- Romania · Brotmin, Glucophage
- Sweden · Forminet, Glucophage
- Slovenia · Aglurab, Glucophage
- Slovakia · Glucophage, Glucophage Xr
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/c2eedf6a-9bde-46a5-b2c7-1389d08ea8ff GET /v1/drugs/c2eedf6a-9bde-46a5-b2c7-1389d08ea8ff?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"unii": {
"unii": "786Z46389E",
"rxcui": "235743",
"inchikey": "OETHQSJEHLVLGH-UHFFFAOYSA-N",
"display_name": "METFORMIN HYDROCHLORIDE",
"substance_type": "chemical",
"ingredient_type": "INGREDIENT SUBSTANCE"
},
"route": "ORAL",
"livertox": {
"summary": null,
"livertox_id": null,
"hepatotoxicity_score": 2
},
"spl_meta": {
"1cb2b2be-595c-4e72-8d2c-c1edc7f85682": {
"match": "brand_token",
"title": "METFORMIN HYDROCHLORIDE TABLET, FILM COATED, EXTENDED RELEASE [GOLDEN STATE MEDICAL SUPPLY, INC.]",
"spl_version": "9",
"published_date": "2026-06-01"
}
},
"productid": "50090-6857_fe4ca567-85b0-4385-8a6a-ac3499990236",
"productndc": "50090-6857",
"dosage_form": "TABLET, FILM COATED",
"orange_book": {
"appl_no": "209882",
"products": [
{
"rs": false,
"rld": false,
"te_code": "AB",
"strength": "500MG",
"product_no": "001",
"approval_date": "Aug 27, 2018"
},
{
"rs": false,
"rld": false,
"te_code": "AB",
"strength": "850MG",
"product_no": "002",
"approval_date": "Aug 27, 2018"
},
{
"rs": false,
"rld": false,
"te_code": "AB",
"strength": "1GM",
"product_no": "003",
"approval_date": "Aug 27, 2018"
}
],
"appl_type": "A"
},
"dea_schedule": null,
"product_type": "HUMAN PRESCRIPTION DRUG",
"substance_name": "METFORMIN HYDROCHLORIDE",
"proprietary_name": "Metformin Hydrochloride",
"active_ingred_unit": "mg/1",
"application_number": "ANDA209882",
"marketing_category": "ANDA",
"nonproprietary_name": "Metformin Hydrochloride",
"start_marketing_date": "20210517",
"active_numerator_strength": "1000"
}See everything about metformin.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.