Netherlands· NL-5aa67a47f394

Endoxan I.V., poeder voor oplossing voor injectie (lyofilisaat) 200 mg, 500 mg, 750 mg, 1000 mg, 2000 mg

A cyclophosphamide product containing cyclofosfamide 1-water + cyclofosfamide 1-water + cyclofosfamide 1-water + cyclofosfamide 1-water, registered in Netherlands by Baxter B.V.. The same ATC class is registered in 17 of our 19 countries.

ATC L01AA01

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about cyclofosfamide 1-water + cyclofosfamide 1-water + cyclofosfamide 1-water + cyclofosfamide 1-waterAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Cyclophosphamide is registered in 17 of 19 countries.

Countries holding a registration under ATC L01AA01 (cyclophosphamide), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
10 of them publish a price we can compare per daily dose

Search cyclophosphamide products by name

Cyclophosphamide · ATC L01AA01

17 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of cyclophosphamide costs, country by country.

Normalised to the WHO defined daily dose (0.25 g), the median price runs from $1.57 in France to $14.12 in Switzerland — a ×9.0 gap.

3 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Cyclophosphamide · price per daily dose (0.25 g)

USD · FX 28 Sept 2026

CH Switzerland$14.12
IT Italy$1.58
FR France$1.57

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: CYCLOFOSFAMIDE 1-WATER + CYCLOFOSFAMIDE 1-WATER + CYCLOFOSFAMIDE 1-WATER + CYCLOFOSFAMIDE 1-WATER
Manufacturer: Baxter B.V.
Country: Netherlands (NL)
ATC code: L01AA01
ATC class: Cyclophosphamide
Defined daily dose: 0.25 g, P
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
08058

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

541 interactions on record for cyclophosphamide.

Graded by severity as the source publishes them — 34 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check cyclophosphamide against other medicines How interaction checks work

Cyclophosphamide · interactions on record

541 records

34 severe
172 moderate
29 minor
304 info

Most severe, free to view

Nalidixic acidJ01MB02severe
CidofovirJ05AB12severe
ThiotepaL01AC01severe
CladribineL01BB04severe

2 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Cyclophosphamide in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All cyclophosphamide products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Cyclophosphamid Sandoz, Endoxan
Belgium · Cyclofosfamide Accord, Cyclophosphamide Hikma
Bulgaria · Cyclophosphamide Sandoz, Ендоксан
Cyprus · Cyclophosphamide Accord, Endoxan
Czechia · Cyclophosphamide Accord, Endoxan
Germany · Cyclophosphamid Accord, Cyclophosphamid Beta
Denmark · Cyclophosphamide Accord, Cyclophosphamide Sandoz
Estonia · Cyclophosphamide Accord, Endoxan
Spain · Ciclofosfamida Accord, Ciclofosfamida Dr. Reddy
Finland · Cyclophosphamide Accord, Sendoxan
France · Cyclophosphamide Accord, Cyclophosphamide Reddy Pharma
United Kingdom (Northern Ireland) · Cyclophosphamide Accord Healthcare, Cyclophosphamide Accord-Uk
Greece · Endoxan
Croatia · Ciklofosfamid Accord, Endoxan
Hungary · Endoxan
Ireland · Cyclophosphamide Monohydrate Seacross, Endoxana
Iceland · Sendoxan
Italy · Ciclofosfamide Accord, Cyclophosphamide Monohydrate Seacross
Lithuania · Cyclophosphamide Accord Healthcare, Endoxan
Luxembourg · Endoxan
Latvia · Cyclophosphamide Accord, Endoxan
Malta · Endoxana, Endoxana Injection
Norway · Cyclophosphamide Accord, Sendoxan
Poland · Cyclophosphamide Accord, Cyclophosphamide Sandoz
Portugal · Ciclofosfamida Accord, Ciclofosfamida Hikma
Romania · Ciclofosfamidă Accord, Ciclofosfamidă Dr. Reddy’s
Sweden · Cyclophosphamide Accord, Cyclophosphamide Sandoz
Slovenia · Endoxan
Slovakia · Endoxan

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/c24a48ad-2286-4a09-8d9a-7c1377fd2cc4
GET /v1/drugs/c24a48ad-2286-4a09-8d9a-7c1377fd2cc4?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Poeder voor oplossing voor injectie",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h08058_smpc.pdf",
  "strength": null,
  "atc_label": "Cyclophosphamide",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg08058",
  "excipients": [
    "MANNITOL (D-) (E 421)",
    "MANNITOL (D-) (E 421)",
    "MANNITOL (D-) (E 421)",
    "MANNITOL (D-) (E 421)",
    "MANNITOL (D-) (E 421)",
    "STIKSTOF (HEAD SPACE) (E 941)",
    "STIKSTOF (HEAD SPACE) (E 941)",
    "STIKSTOF (HEAD SPACE) (E 941)",
    "STIKSTOF (HEAD SPACE) (E 941)",
    "STIKSTOF (HEAD SPACE) (E 941)"
  ],
  "substances": [
    "CYCLOFOSFAMIDE 1-WATER",
    "CYCLOFOSFAMIDE 1-WATER",
    "CYCLOFOSFAMIDE 1-WATER",
    "CYCLOFOSFAMIDE 1-WATER",
    "CYCLOFOSFAMIDE 1-WATER"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h08058.pdf",
  "authorised_at": "1981/10/22",
  "procedure_number": null,
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "08058",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about cyclophosphamide.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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