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Ireland· IE-PA-EU/1/13/879/001-003

GIOTRIF 20 mg film-coated tablets

A afatinib product containing afatinib-dimaleate, registered in Ireland by Boehringer Ingelheim International GmbH.

ATC L01XE13

Checked against HPRA (Ireland) on

Informational only — not a medical device.

SOURCE REGISTER · IEHPRA (Ireland)normalisedGIOTRIF 20 mg film-coated tabletsATCL01XE13REGISTER NO.IE-PA-EU/1/13/879/001…PACKS LISTED1CHECKEDSeptember 28, 2026

The record

At a glance

HPRA (Ireland)
Active substance
Afatinib-dimaleate
Manufacturer
Boehringer Ingelheim International GmbH
Country
Ireland (IE)
ATC code
L01XE13
ATC class
Afatinib
Reimbursed
Not published by this register
Source register
HPRA (Ireland)
Last checked
September 28, 2026

Packs & prices · 1

  • ie_pa_number
    EU/1/13/879/001-003

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

170 interactions on record for afatinib.

Graded by severity as the source publishes them — 10 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Afatinib · interactions on record

170 records

  • 10 severe
  • 158 moderate
  • 2 minor

Most severe, free to view

  • MipomersenC10AX11severe
  • LomitapideC10AX12severe
  • PexidartinibL01EX15severe
  • OzanimodL04AE02severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Afatinib in 11 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All afatinib products

Authorised across Europe · EMA

The same active substance is authorised in 8 EEA countries. Names it is sold under:

  • Cyprus · Afatinib Afatinib, Afatinib Sapiens
  • Greece · Webrix
  • Iceland · Giotrif
  • Liechtenstein · Giotrif
  • Latvia · Afatinib, Afatinib Lotus
  • Malta · Afatinib Lotus
  • Norway · Giotrif
  • Sweden · Afatinib Lotus, Webrix

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/c0f2d511-2581-4743-8596-5c986293c39a
GET /v1/drugs/c0f2d511-2581-4743-8596-5c986293c39a?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Film-coated tablet",
  "routes": [
    "Oral use"
  ],
  "source": "hpra",
  "atc_all": [
    "L01XE",
    "L01XE13"
  ],
  "strength": null,
  "pa_number": "EU/1/13/879/001-003",
  "substances": [
    "Afatinib-dimaleate"
  ],
  "legal_basis": "Full application (Article 8(3) of Directive No 2001/83/EC)",
  "market_info": "Unknown",
  "authorised_at": "25/09/2013",
  "dispensing_status": "Product subject to prescription which may not be renewed (A)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": null
}

See everything about afatinib.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.