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Japan· JP-3999016M1021

メトトレキサート

A methotrexate product containing メトトレキサート, registered in Japan by ファイザー, on the national reimbursement list. The same ATC class is registered in 12 of our 19 countries.

On Japan’s NHI price listATC L01BA01

Checked against MHLW / PMDA (Japan) on

Informational only — not a medical device.

SOURCE REGISTER · JPMHLW / PMDA (Japan)normalisedメトトレキサートATCL01BA01REGISTER NO.JP-3999016M1021PACKS LISTED0CHECKEDSeptember 25, 2026

Where it is registered

Methotrexate is registered in 12 of 19 countries.

Countries holding a registration under ATC L01BA01 (methotrexate), each read from that country’s own register.

  • This record: Japan, from MHLW / PMDA (Japan)
  • 7 of them publish a price we can compare per daily dose

Methotrexate · ATC L01BA01

12 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Japan
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

MHLW / PMDA (Japan)
Active substance
メトトレキサート
Manufacturer
ファイザー
Country
Japan (JP)
ATC code
L01BA01
ATC class
Methotrexate
Reimbursed
Yes
Source register
MHLW / PMDA (Japan)
Last checked
September 25, 2026

Packs & prices · 0

No packs listed by the register for this record.

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

949 interactions on record for methotrexate.

Graded by severity as the source publishes them — 107 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Methotrexate · interactions on record

949 records

  • 107 severe
  • 466 moderate
  • 17 minor
  • 309 info

Most severe, free to view

  • OmeprazoleA02BC01severe
  • PantoprazoleA02BC02severe
  • LansoprazoleA02BC03severe
  • RabeprazoleA02BC04severe

50 more interactions with mechanism and management, from a commercially licensed source.

Sign in to check
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of MHLW / PMDA (Japan). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/bcdd29c8-6ff6-44a0-8ddc-b80ab5867dd7
GET /v1/drugs/bcdd29c8-6ff6-44a0-8ddc-b80ab5867dd7?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "spec": "2mg1カプセル",
  "marks": "局",
  "source": "mhlw",
  "remarks": null,
  "yj_code": "3999016M1021",
  "category": "内用薬",
  "price_yen": 77.9,
  "generic_name": "メトトレキサート",
  "product_name_jp": null,
  "therapeutic_class": "3999",
  "transitional_expiry": null
}

See everything about methotrexate.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.