Netherlands· NL-1dc0dfc5f3ac
Urokinase Syner-Medica 25.000 IE, poeder voor oplossing voor injectie/infusie
A urokinase product containing urokinase, registered in Netherlands by Syner-Medica B.V.. The same ATC class is registered in 6 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Urokinase is registered in 6 of 19 countries.
Countries holding a registration under ATC B01AD04 (urokinase), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 4 of them publish a price we can compare per daily dose
Urokinase · ATC B01AD04
6 / 19 countries
- Belgiumprice
- Finlandprice
- Japan
- Netherlands
- Polandprice
- Switzerlandprice
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- UROKINASE
- Manufacturer
- Syner-Medica B.V.
- Country
- Netherlands (NL)
- ATC code
- B01AD04
- ATC class
- Urokinase
- Defined daily dose
- 3 MIO, E
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id122409
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
130 interactions on record for urokinase.
Graded by severity as the source publishes them — 46 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Urokinase · interactions on record
130 records
- 46 severe
- 84 moderate
Most severe, free to view
- WarfarinB01AA03severe
- HeparinB01AB01severe
- DalteparinB01AB04severe
- EnoxaparinB01AB05severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Urokinase in 8 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomSyner-KINASE 10,000unit powder for solution for injection vialsSyner-Med (Pharmaceutical Products) Ltd
- BelgiumActosolv 100000 IUEumedica Pharmaceuticals
- SpainUROKINASE TEOFARMA 100.000 UI. POLVO Y DISOLVENTE PARA SOLUCION PARA PERFUSIONTeofarma S.R.L.
- FranceACTOSOLV 100 000 UI, poudre pour solution injectable/pour perfusionEUMEDICA PHARMACEUTICALS (ALLEMAGNE)
- PolandUrokinase medacPharma-Zentrale GmbH
- GermanyRheotrombEumedica / Belgium
- FinlandUrokinase MedacMedac Gesellschaft Für Klinische Spezialpräparate mbH
- Japanウロキナーゼ持田製薬
Authorised across Europe · EMA
The same active substance is authorised in 9 EEA countries. Names it is sold under:
- Austria · Urokinase Medac
- Belgium · Actosolv, Urokinase Syner-Medica
- Germany · Rheotromb, Syner-Kinase
- Spain · Urokinase Teofarma, Uroquinasa Syner Medica
- France · Actosolv, Therasolv
- United Kingdom (Northern Ireland) · Syner-Kinase
- Italy · Urochinasi Eg, Urokinasi Pfizer
- Luxembourg · Actosolv
- Poland · Urokinase Medac
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/bcdae397-e17e-4707-a5ee-ad73d39ba323 GET /v1/drugs/bcdae397-e17e-4707-a5ee-ad73d39ba323?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Poeder voor oplossing voor injectie of infusie",
"route": "Intraveneus gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h122409_smpc.pdf",
"strength": null,
"atc_label": "Urokinase",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg122409",
"excipients": [
"DINATRIUMEDETAAT 2-WATER",
"DINATRIUMWATERSTOFFOSFAAT 12-WATER (E 339)",
"MANNITOL (D-) (E 421)",
"NATRIUMHYDROXIDE (E 524)"
],
"substances": [
"UROKINASE"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h122409.pdf",
"authorised_at": "2019/11/14",
"procedure_number": "NL/H/4884/002",
"dispensing_status": "Uitsluitend recept",
"registration_number": "122409",
"additional_monitoring": "N"
}See everything about urokinase.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.