Netherlands· NL-7b90902098b1

Levodopa/Carbidopa/Entacapone Orion 100 mg/25 mg/200 mg filmomhulde tabletten

A levodopa, decarboxylasehemmer und comt-hemmer product containing carbidopa 1-water + entacapone + levodopa, registered in Netherlands by Orion Corporation. The same ATC class is registered in 12 of our 19 countries.

ATC N04BA03

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about carbidopa 1-water + entacapone + levodopaAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Levodopa, decarboxylasehemmer und comt-hemmer is registered in 12 of 19 countries.

Countries holding a registration under ATC N04BA03 (levodopa, decarboxylasehemmer und comt-hemmer), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
8 of them publish a price we can compare per daily dose

Search levodopa, decarboxylasehemmer und comt-hemmer products by name

Levodopa, decarboxylasehemmer und comt-hemmer · ATC N04BA03

12 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of levodopa, decarboxylasehemmer und comt-hemmer costs, country by country.

Normalised to the WHO defined daily dose (0.45 g), the median price runs from $1.36 in Italy to $5.49 in Switzerland — a ×4.0 gap.

2 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Levodopa, decarboxylasehemmer und comt-hemmer · price per daily dose (0.45 g)

USD · FX 28 Sept 2026

CH Switzerland$5.49
IT Italy$1.36

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: CARBIDOPA 1-WATER + ENTACAPONE + LEVODOPA
Manufacturer: Orion Corporation
Country: Netherlands (NL)
ATC code: N04BA03
ATC class: Levodopa, Decarboxylasehemmer und COMT-Hemmer
Defined daily dose: 0.45 g, O
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
EU/1/11/706

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

158 interactions on record for levodopa, decarboxylasehemmer und comt-hemmer.

Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check levodopa, decarboxylasehemmer und comt-hemmer against other medicines How interaction checks work

Levodopa, decarboxylasehemmer und comt-hemmer · interactions on record

158 records

4 severe
122 moderate
14 minor

Most severe, free to view

ProcarbazineL01XB01severe
OzanimodL04AA38severe
OzanimodL04AE02severe
Methylthioninium chlorideV03AB17severe

18 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Levodopa, decarboxylasehemmer und comt-hemmer in 7 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All levodopa, decarboxylasehemmer und comt-hemmer products

Authorised across Europe · EMA

The same active substance is authorised in 25 EEA countries. Names it is sold under:

Austria · Lecigimon, Trigelan
Belgium · Lecigen
Bulgaria · Лесигон
Czechia · Lecigimon, Trigelan
Germany · Lecigon, Levodopa/Carbidopa/Entacapon Abz
Denmark · Lecigon, Levodopa/Carbidopa/Entacapone G.L. Pharma
Estonia · Levodopa/Carbidopa/Entacapone Teva
Spain · Lecigon
Finland · Lecigon, Lecigon,
France · Lecigimon, Levodopa/Carbidopa/Entacapone Teva
United Kingdom (Northern Ireland) · Lecigon
Greece · Levodopa+carbidopa+entacapone Mylan
Croatia · Lecigon
Hungary · Lecigon, Levodopa/Carbidopa/Entacapone Teva
Ireland · Lecigon
Italy · Lecigimon, Levodopa/Carbidopa/Entacapone Mylan
Luxembourg · Lecigimon
Latvia · Levodopa/Carbidopa/Entacapone Teva
Norway · Lecigon
Poland · Lecigon
Portugal · Lecigon
Romania · Lecigon, Levodopa/Carbidopa/Entacaponă Teva
Sweden · Lecigon, Levodopa/Carbidopa/Entacapone Pharmexon
Slovenia · Lecigon
Slovakia · Lecigon, Trigelan

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/bc09fd44-7a19-40d2-82f0-3a02c09fbb61
GET /v1/drugs/bc09fd44-7a19-40d2-82f0-3a02c09fbb61?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Filmomhulde tablet",
  "route": "Oraal gebruik",
  "soort": null,
  "source": "cbg_meb",
  "smpc_url": "https://www.ema.europa.eu/en/documents/product-information/levodopa/carbidopa/entacapone-orion-epar-product-information_nl.pdf",
  "strength": null,
  "atc_label": "Levodopa, Decarboxylase Inhibitor And Comt Inhibitor",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp109827",
  "excipients": [
    "CROSCARMELLOSE  NATRIUM  (E 468)",
    "GLYCEROL 85 PER CENT (E 422)",
    "HYPROMELLOSE (E 464)",
    "IJZEROXIDE GEEL (E 172)",
    "IJZEROXIDE ROOD  (E 172)",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MANNITOL (D-) (E 421)",
    "MAÏSZETMEEL",
    "POLYSORBAAT 80 (E 433)",
    "POVIDON (E 1201)",
    "SACCHAROSE",
    "TITAANDIOXIDE (E 171)"
  ],
  "substances": [
    "CARBIDOPA 1-WATER",
    "ENTACAPONE",
    "LEVODOPA"
  ],
  "leaflet_url": null,
  "authorised_at": "2011/08/25",
  "procedure_number": "EMEA/H/C/002441",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "EU/1/11/706",
  "additional_monitoring": "N"
}

API reference MCP server Plans

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This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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