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Netherlands· NL-f894deea5e2f

Depakine Chronosphere 1000 mg, granulaat met gereguleerde afgifte

A valproic acid product containing natriumvalproaat + valproïnezuur, registered in Netherlands by Sanofi B.V.. The same ATC class is registered in 16 of our 19 countries.

ATC N03AG01

Checked against CBG-MEB (Netherlands) on

Informational only — not a medical device.

SOURCE REGISTER · NLCBG-MEB (Netherlands)normalisedDepakine Chronosphere 1000 mg, granul…ATCN03AG01REGISTER NO.NL-f894deea5e2fPACKS LISTED1CHECKEDSeptember 29, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about natriumvalproaat + valproïnezuurAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Valproic acid is registered in 16 of 19 countries.

Countries holding a registration under ATC N03AG01 (valproic acid), each read from that country’s own register.

  • This record: Netherlands, from CBG-MEB (Netherlands)
  • 9 of them publish a price we can compare per daily dose
Search valproic acid products by name

Valproic acid · ATC N03AG01

16 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Germany
  • Icelandprice
  • Ireland
  • Italyprice
  • Japan
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of valproic acid costs, country by country.

Normalised to the WHO defined daily dose (1.5 g), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown
Open the full comparison — free accountDrug prices for market access

Valproic acid · price per daily dose (1.5 g)

USD · FX 28 Sept 2026

  • CH Switzerland$1.61
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)
Active substance
NATRIUMVALPROAAT + VALPROÏNEZUUR
Manufacturer
Sanofi B.V.
Country
Netherlands (NL)
ATC code
N03AG01
ATC class
Valproic acid
Defined daily dose
1.5 g, O
Reimbursed
Not published by this register
Source register
CBG-MEB (Netherlands)
Last checked
September 29, 2026

Packs & prices · 1

  • cbg_meb_id
    30763

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

391 interactions on record for valproic acid.

Graded by severity as the source publishes them — 9 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check valproic acid against other medicinesHow interaction checks work

Valproic acid · interactions on record

391 records

  • 9 severe
  • 132 moderate
  • 23 minor
  • 189 info

Most severe, free to view

  • Glycerol phenylbutyrateA16AX09severe
  • BexaroteneL01XF03severe
  • VorinostatL01XH01severe
  • BexarotenL01XX25severe

38 more interactions with mechanism and management, from a commercially licensed source.

Sign in to check
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same class

Other records under N03AG01

Valproic acid, as other registers publish it.

All valproic acid products

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/b9480f95-0405-4ea8-bcee-354400cd812c
GET /v1/drugs/b9480f95-0405-4ea8-bcee-354400cd812c?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Granulaat met gereguleerde afgifte",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h30763_smpc.pdf",
  "strength": null,
  "atc_label": "Valproic Acid",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg30763",
  "excipients": [
    "GLYCEROLDIBEHENAAT",
    "PARAFFINE, HARD (E 905)",
    "SILICIUMDIOXIDE, GEHYDRATEERD (E 551)"
  ],
  "substances": [
    "NATRIUMVALPROAAT",
    "VALPROÏNEZUUR"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h30763.pdf",
  "authorised_at": "2005/10/21",
  "procedure_number": null,
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "30763",
  "additional_monitoring": "Y"
}
API referenceMCP serverPlans

See everything about valproic acid.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console