Ireland· IE-PA-PA2241/001/002
Leydex 25 mg Orodispersible tablets
A clozapine product containing clozapine, registered in Ireland by Leyden Delta BV. The same ATC class is registered in 17 of our 19 countries.
Checked against HPRA (Ireland) on
Informational only — not a medical device.
Where it is registered
Clozapine is registered in 17 of 19 countries.
Countries holding a registration under ATC N05AH02 (clozapine), each read from that country’s own register.
- This record: Ireland, from HPRA (Ireland)
- 10 of them publish a price we can compare per daily dose
Clozapine · ATC N05AH02
17 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of clozapine costs, country by country.
Normalised to the WHO defined daily dose (0.3 g), the median price runs from $1.63 in France to $2.78 in Switzerland — a ×1.7 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Clozapine · price per daily dose (0.3 g)
USD · FX 28 Sept 2026
- CH Switzerland$2.78
- IT Italy$2.38
- FR France$1.63
The record
At a glance
HPRA (Ireland)- Active substance
- Clozapine
- Manufacturer
- Leyden Delta BV
- Country
- Ireland (IE)
- ATC code
- N05AH02
- ATC class
- Clozapine
- Defined daily dose
- 0.3 g, O
- Reimbursed
- Not published by this register
- Source register
- HPRA (Ireland)
- Last checked
- September 28, 2026
Packs & prices · 1
- ie_pa_numberPA2241/001/002
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
620 interactions on record for clozapine.
Graded by severity as the source publishes them — 306 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Clozapine · interactions on record
620 records
- 306 severe
- 197 moderate
- 4 minor
- 61 info
Most severe, free to view
- PapaverineA03AD01severe
- MetoclopramideA03FA01severe
- CisaprideA03FA02severe
- OndansetronA04AA01severe
52 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Clozapine in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomClozapine 25mg orodispersible tablets sugar freeViatris UK Healthcare Ltd
- United StatesClozapineAurobindo Pharma Limited
- SpainNEMEA 25 MG COMPRIMIDOS BUCODISPERSABLES EFGAdamed Laboratorios S.L.U.
- NorwayZaponexLeyden Delta
- PolandAyupilSynthon B.V.
- FinlandLeponexViatris Oy
- NetherlandsAyupine 100 mg, orodispergeerbare tablettenSynthon B.V.
- CzechiaCLOZAPIN DESITINDesitin Arzneimittel GmbH, Hamburg
Authorised across Europe · EMA
The same active substance is authorised in 29 EEA countries. Names it is sold under:
- Austria · Clozapin Accord, Clozapin Ratiopharm
- Belgium · Clozapine Sandoz, Leponex
- Bulgaria · Ексклоза, Клозапин Акорд
- Cyprus · Clozapine Accord, Clozarem
- Czechia · Clozapin Desitin, Leponex
- Germany · Clozapin 1a-Pharma, Clozapin Abz
- Denmark · Clozapin Accord, Clozapin Hexal
- Estonia · Clozapine Accord, Leponex
- Spain · Clozabrain, Clozapina Aurovitas
- Finland · Clozapine Accord, Clozapine Stada
- France · Clozapine Accord, Clozapine Aristo
- United Kingdom (Northern Ireland) · Clozapine, Clozapine Viatris
- Greece · Leponex
- Croatia · Klozapin Accord, Klozapin Alpha-Medical
- Hungary · Clozapine Gerot, Clozapine Stada
- Iceland · Clozapin Medical, Clozapine Actavis
- Italy · Clozapina Accord, Clozapina Aurobindo
- Lithuania · Clozapine Accord, Leponex
- Luxembourg · Leponex
- Latvia · Clozapine Accord, Leponex
- Malta · Clozarem
- Netherlands · Ayupine, Clozapine Accord
- Norway · Clozapin Hexal, Clozapine Accord
- Poland · Clopizam, Clozapine Hasco
- Portugal · Clozapina Aristo, Clozapina Aurovitas
- Romania · Leponex
- Sweden · Clozapine Accord, Clozapine Actavis
- Slovenia · Klozapin Accord, Leponex
- Slovakia · Clozapine Accord, Leponex
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/b89661fb-8d39-41cf-b515-9e06c4d6891a GET /v1/drugs/b89661fb-8d39-41cf-b515-9e06c4d6891a?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Orodispersible tablet",
"routes": [
"Oral use"
],
"source": "hpra",
"atc_all": [
"N05AH",
"N05AH02"
],
"strength": null,
"pa_number": "PA2241/001/002",
"substances": [
"Clozapine"
],
"legal_basis": "Hybrid application (Article 10(3) of Directive No 2001/83/EC)",
"market_info": "Unknown",
"authorised_at": "12/04/2019",
"dispensing_status": "Product subject to prescription which may not be renewed (A)",
"registration_status": "AU",
"supply_legal_status": "Supply through pharmacies only",
"interchangeable_code": null
}See everything about clozapine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.