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United Kingdom· GB-APID-42510011000001103

Kaftrio 75mg/50mg/100mg granules sachets

A ivacaftor, tezacaftor and elexacaftor product containing ivacaftor + tezacaftor + elexacaftor, registered in United Kingdom by Vertex Pharmaceuticals (Europe) Ltd. The same ATC class is registered in 14 of our 19 countries.

ATC R07AX32

Checked against NHS dm+d (United Kingdom) on

Informational only — not a medical device.

SOURCE REGISTER · GBNHS dm+d (United Kingdom)normalisedKaftrio 75mg/50mg/100mg granules sach…ATCR07AX32REGISTER NO.GB-APID-4251001100000…PACKS LISTED2CHECKEDSeptember 13, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about ivacaftor + tezacaftor + elexacaftorAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Ivacaftor, tezacaftor and elexacaftor is registered in 14 of 19 countries.

Countries holding a registration under ATC R07AX32 (ivacaftor, tezacaftor and elexacaftor), each read from that country’s own register.

  • This record: United Kingdom, from NHS dm+d (United Kingdom)
  • 9 of them publish a price we can compare per daily dose
Search ivacaftor, tezacaftor and elexacaftor products by name

Ivacaftor, tezacaftor and elexacaftor · ATC R07AX32

14 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Spainprice
  • Switzerlandprice
  • United Kingdom
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

NHS dm+d (United Kingdom)
Active substance
Ivacaftor + Tezacaftor + Elexacaftor
Manufacturer
Vertex Pharmaceuticals (Europe) Ltd
Country
United Kingdom (GB)
ATC code
R07AX32
ATC class
Ivacaftor, tezacaftor and elexacaftor
Reimbursed
Not published by this register
Source register
NHS dm+d (United Kingdom)
Last checked
September 13, 2026

Packs & prices · 2

  • gtin
    00351167157404
  • gtin
    03400930280355

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

14 interactions on record for ivacaftor, tezacaftor and elexacaftor.

Graded by severity as the source publishes them — 14 moderate. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check ivacaftor, tezacaftor and elexacaftor against other medicinesHow interaction checks work

Ivacaftor, tezacaftor and elexacaftor · interactions on record

14 records

  • 14 moderate

Most severe, free to view

  • RifaximinA07AA11moderate
  • EmpagliflozinA10BK03moderate
  • RepaglinideA10BX02moderate
  • EmpagliflozinA10BX12moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Ivacaftor, tezacaftor and elexacaftor in 12 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All ivacaftor, tezacaftor and elexacaftor products

Authorised across Europe · EMA

The same active substance is authorised in 3 EEA countries. Names it is sold under:

  • Iceland · Kaftrio
  • Liechtenstein · Kaftrio
  • Norway · Kaftrio

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/b721e425-70b8-4f77-906a-a545117fd08b
GET /v1/drugs/b721e425-70b8-4f77-906a-a545117fd08b?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "apid": "42510011000001103",
  "desc": "Kaftrio 75mg/50mg/100mg granules sachets (Vertex Pharmaceuticals (Europe) Ltd)",
  "form": "Oral granules",
  "vpid": "42545111000001102",
  "source": "dmd",
  "vtm_id": "827103004",
  "strength": "50 mg",
  "substance": "Ivacaftor + Tezacaftor + Elexacaftor",
  "ingredient": "Tezacaftor",
  "supplier_code": "21148411000001105"
}
API referenceMCP serverPlans

See everything about ivacaftor, tezacaftor and elexacaftor.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console