Netherlands· NL-50032af51293

RINVOQ 45 mg tabletten met verlengde afgifte

A upadacitinib product containing upadacitinib 0,5-water, registered in Netherlands by AbbVie Deutschland GmbH & Co. KG. The same ATC class is registered in 13 of our 19 countries.

ATC L04AF03

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about upadacitinib 0,5-waterAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Upadacitinib is registered in 13 of 19 countries.

Countries holding a registration under ATC L04AF03 (upadacitinib), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
8 of them publish a price we can compare per daily dose

Search upadacitinib products by name

Upadacitinib · ATC L04AF03

13 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Japan
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of upadacitinib costs, country by country.

Normalised to the WHO defined daily dose (15 mg), so markets compare like for like.

1 market with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Upadacitinib · price per daily dose (15 mg)

USD · FX 28 Sept 2026

CH Switzerland$32.01

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: UPADACITINIB 0,5-WATER
Manufacturer: AbbVie Deutschland GmbH & Co. KG
Country: Netherlands (NL)
ATC code: L04AF03
ATC class: Upadacitinib
Defined daily dose: 15 mg, O
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
EU/1/19/1404

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

407 interactions on record for upadacitinib.

Graded by severity as the source publishes them — 337 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check upadacitinib against other medicines How interaction checks work

Upadacitinib · interactions on record

407 records

337 severe
63 moderate
7 minor

Most severe, free to view

PrednisoloneA07EA01severe
HydrocortisoneA07EA02severe
PrednisoneA07EA03severe
BetamethasoneA07EA04severe

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Upadacitinib in 9 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All upadacitinib products

Authorised across Europe · EMA

The same active substance is authorised in 4 EEA countries. Names it is sold under:

United Kingdom (Northern Ireland) · Rinvoq
Iceland · Rinvoq
Liechtenstein · Rinvoq
Norway · Rinvoq

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/b662aad2-812b-4e62-bb1e-f25463a1d8a6
GET /v1/drugs/b662aad2-812b-4e62-bb1e-f25463a1d8a6?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Tablet met verlengde afgifte",
  "route": "Oraal gebruik",
  "soort": null,
  "source": "cbg_meb",
  "smpc_url": "https://www.ema.europa.eu/en/documents/product-information/rinvoq-epar-product-information_nl.pdf",
  "strength": null,
  "atc_label": "Upadacitinib",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp130601",
  "excipients": [
    "CELLULOSE, MICROKRISTALLIJN (E 460(i))",
    "HYPROMELLOSE 2208 (Release controlling polymer), K4M (E 464)",
    "IJZEROXIDE GEEL (E 172)",
    "IJZEROXIDE ROOD  (E 172)",
    "MACROGOL 3350",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MANNITOL (D-) (E 421)",
    "POLYVINYLALCOHOL (E 1203)",
    "SILICIUMDIOXIDE (E 551)",
    "TALK (E 553b)",
    "TITAANDIOXIDE (E 171)",
    "WIJNSTEENZUUR, (L (+) Vorm) (E 334)"
  ],
  "substances": [
    "UPADACITINIB 0,5-WATER"
  ],
  "leaflet_url": null,
  "authorised_at": "2019/12/16",
  "procedure_number": "EMEA/H/C/004760",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "EU/1/19/1404",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about upadacitinib.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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