United Kingdom· GB-APID-2892211000001108

Uniphyllin 400mg prolonged-release tablets

A theophylline product containing theophylline, registered in United Kingdom by Ennogen Healthcare International Ltd. The same ATC class is registered in 12 of our 19 countries.

ATC R03DA04

Checked against NHS dm+d (United Kingdom) on September 13, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about theophyllineAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Theophylline is registered in 12 of 19 countries.

Countries holding a registration under ATC R03DA04 (theophylline), each read from that country’s own register.

This record: United Kingdom, from NHS dm+d (United Kingdom)
6 of them publish a price we can compare per daily dose

Search theophylline products by name

Theophylline · ATC R03DA04

12 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Germany
Ireland
Japan
Norwayprice
Polandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of theophylline costs, country by country.

Normalised to the WHO defined daily dose (0.4 g), so markets compare like for like.

1 market with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Theophylline · price per daily dose (0.4 g)

USD · FX 28 Sept 2026

US United States$0.71 (acquisition cost)

Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

NHS dm+d (United Kingdom)

Active substance: Theophylline
Manufacturer: Ennogen Healthcare International Ltd
Country: United Kingdom (GB)
ATC code: R03DA04
ATC class: Theophylline
Defined daily dose: 0.4 g, O
Reimbursed: Not published by this register
Source register: NHS dm+d (United Kingdom)
Last checked: September 13, 2026

Packs & prices · 4

gtin
5012854061347
gtin
05012854061347
gtin
05060254925646
gtin
05056682201148

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

438 interactions on record for theophylline.

Graded by severity as the source publishes them — 34 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check theophylline against other medicines How interaction checks work

Theophylline · interactions on record

438 records

34 severe
222 moderate
45 minor
132 info

Most severe, free to view

MexiletineC01BB02severe
RiociguatC02KX05severe
PindololC07AA03severe
PropranololC07AA05severe

5 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Theophylline in 13 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All theophylline products

Authorised across Europe · EMA

The same active substance is authorised in 25 EEA countries. Names it is sold under:

Austria · Theospirex, Theospirex Retard
Belgium · Xanthium
Bulgaria · Теотард
Cyprus · Theo-Dur
Czechia · Euphyllin Cr N
Germany · Afpred Forte-Theo, Bronchoretard
Denmark · Theo-Dur, Unixan
Estonia · Teotard
Spain · Elixifilin, Teromol Retard
Finland · Retafyllin
France · Dilatrane, Tedralan
Greece · Theo-Bros, Theo-Dur
Croatia · Teotard
Hungary · Theophyllini Fono Vii. Naturland, Theophyllini Fono Viii. Parma
Ireland · Uniphyllin
Lithuania · Teotard
Luxembourg · Xanthium
Latvia · Teotard
Norway · Theo-Dur
Poland · Euphyllin Long, Theophyllinum Tramco
Portugal · Unicontin
Romania · Teotard
Sweden · Theo-Dur
Slovenia · Teotard
Slovakia · Euphyllin Cr N 200, Euphyllin Cr N 300

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/b5d18b68-d7c7-475d-9966-24960a4bf488
GET /v1/drugs/b5d18b68-d7c7-475d-9966-24960a4bf488?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "apid": "2892211000001108",
  "desc": "Uniphyllin 400mg prolonged-release tablets (Ennogen Healthcare International Ltd)",
  "form": "Modified-release tablet",
  "vpid": "35918111000001108",
  "source": "dmd",
  "vtm_id": "777737000",
  "strength": "400 mg",
  "substance": "Theophylline",
  "ingredient": "Theophylline",
  "supplier_code": "17632511000001109"
}

API reference MCP server Plans

See everything about theophylline.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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