United Kingdom· GB-APID-20914611000001101
Leflunomide 20mg tablets
A leflunomide product containing leflunomide, registered in United Kingdom by Zentiva Pharma UK Ltd. The same ATC class is registered in 15 of our 19 countries.
Checked against NHS dm+d (United Kingdom) on
Informational only — not a medical device.
Where it is registered
Leflunomide is registered in 15 of 19 countries.
Countries holding a registration under ATC L04AK01 (leflunomide), each read from that country’s own register.
- This record: United Kingdom, from NHS dm+d (United Kingdom)
- 9 of them publish a price we can compare per daily dose
Leflunomide · ATC L04AK01
15 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of leflunomide costs, country by country.
Normalised to the WHO defined daily dose (20 mg), the median price runs from $0.47 in United States to $2.13 in Italy — a ×4.5 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Leflunomide · price per daily dose (20 mg)
USD · FX 28 Sept 2026
- IT Italy$2.13
- CH Switzerland$1.48
- US United States$0.47 (acquisition cost)
The record
At a glance
NHS dm+d (United Kingdom)- Active substance
- Leflunomide
- Manufacturer
- Zentiva Pharma UK Ltd
- Country
- United Kingdom (GB)
- ATC code
- L04AK01
- ATC class
- Leflunomide
- Defined daily dose
- 20 mg, O
- Reimbursed
- Not published by this register
- Source register
- NHS dm+d (United Kingdom)
- Last checked
- September 13, 2026
Packs & prices · 1
- gtin5000283654483
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
805 interactions on record for leflunomide.
Graded by severity as the source publishes them — 537 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Leflunomide · interactions on record
805 records
- 537 severe
- 47 moderate
- 7 minor
- 214 info
Most severe, free to view
- ClotrimazoleA01AB18severe
- Chenodeoxycholic acidA05AA01severe
- PrednisoloneA07EA01severe
- HydrocortisoneA07EA02severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Leflunomide in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesleflunomideBryant Ranch Prepack
- CanadaACCEL-LEFLUNOMIDEACCEL PHARMA INC
- SwitzerlandLeflunomid-Mepha
- SpainLEFLUNOMIDA TILLOMED 20 MG COMPRIMIDOS EFGLaboratorios Tillomed Spain S.L.
- NetherlandsLeflunomide Tillomed 20 mg, tablettenTillomed Pharma GmbH
- NorwayLeflunomide zentivaZentiva
- CzechiaARAVASanofi-Aventis Deutschland GmbH, Frankfurt am Main
- BelgiumArava 10 mgPI Pharma
Authorised across Europe · EMA
The same active substance is authorised in 26 EEA countries. Names it is sold under:
- Austria · Leflunomid Stada
- Belgium · Leflunomid Sandoz, Leflunomide Ab
- Bulgaria · Багеда
- Cyprus · Arotan
- Czechia · Leflon, Leflugen
- Germany · Leflon, Leflunomid 1 A Pharma
- Denmark · Leflunomid, Leflunomid "egis"
- Estonia · Leflunomide Elvim
- Spain · Lefluartil, Leflunomida Aurovitas
- Finland · Leflunomide Orion, Leflunomide Stada
- France · Leflunomide Arrow, Leflunomide Biogaran
- Greece · Lefid, Lefluonia
- Hungary · Leflunomid Sandoz
- Ireland · Leflunomide Aspire Pharma (Malta)
- Iceland · Arava, Leflunomide Medac
- Italy · Leflunomide Aurobindo, Leflunomide Mylan
- Liechtenstein · Arava, Leflunomide Medac
- Lithuania · Leflunomide Elvim, Leflunomide Sandoz
- Latvia · Leflunomide Elvim, Leflunomide Sandoz
- Malta · Leflunomide Normon
- Netherlands · Leflunomide Aurobindo, Leflunomide Cf
- Norway · Arava, Leflunomide Medac
- Poland · Leflunomid Bluefish, Leflunomid Egis
- Portugal · Leflunomida Farmoz, Leflunomida Generis
- Romania · Leflon, Leflunomidă Arena
- Sweden · Leflunomid Bluefish
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/b29799b8-1ce0-4d36-a8be-275aa811f30b GET /v1/drugs/b29799b8-1ce0-4d36-a8be-275aa811f30b?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"apid": "20914611000001101",
"desc": "Leflunomide 20mg tablets (Zentiva Pharma UK Ltd)",
"form": "Oral tablet",
"vpid": "41790611000001106",
"source": "dmd",
"vtm_id": "776493008",
"strength": "20 mg",
"substance": "Leflunomide",
"ingredient": "Leflunomide",
"supplier_code": "9043311000001106"
}See everything about leflunomide.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.