Netherlands· NL-f3212fdd9889
Natriumvalproaat Sandoz Chrono 500, tabletten met verlengde afgifte 500 mg
A valproic acid product containing natriumvalproaat + natriumvalproaat + valproïnezuur, registered in Netherlands by Sandoz B.V.. The same ATC class is registered in 16 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Valproic acid is registered in 16 of 19 countries.
Countries holding a registration under ATC N03AG01 (valproic acid), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 9 of them publish a price we can compare per daily dose
Valproic acid · ATC N03AG01
16 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of valproic acid costs, country by country.
Normalised to the WHO defined daily dose (1.5 g), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Valproic acid · price per daily dose (1.5 g)
USD · FX 28 Sept 2026
- CH Switzerland$1.61
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- NATRIUMVALPROAAT + NATRIUMVALPROAAT + VALPROÏNEZUUR
- Manufacturer
- Sandoz B.V.
- Country
- Netherlands (NL)
- ATC code
- N03AG01
- ATC class
- Valproic acid
- Defined daily dose
- 1.5 g, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id33300
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
391 interactions on record for valproic acid.
Graded by severity as the source publishes them — 9 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Valproic acid · interactions on record
391 records
- 9 severe
- 132 moderate
- 23 minor
- 189 info
Most severe, free to view
- Glycerol phenylbutyrateA16AX09severe
- BexaroteneL01XF03severe
- VorinostatL01XH01severe
- BexarotenL01XX25severe
38 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same class
Other records under N03AG01
Valproic acid, as other registers publish it.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/b0afbb80-9b62-4f70-bd07-ed7ddd7c2b01 GET /v1/drugs/b0afbb80-9b62-4f70-bd07-ed7ddd7c2b01?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tablet met verlengde afgifte",
"route": "Oraal gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h33300_smpc.pdf",
"strength": null,
"atc_label": "Valproic Acid",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg33300",
"excipients": [
"COPOLYMEER VAN ETHYLACRYLAAT-METHACRYLZUUR (1:1)",
"ETHYLCELLULOSE (E 462)",
"HYPROMELLOSE (E 464)",
"MACROGOL 6000",
"SACCHAROIDE NATRIUM X-WATER (E 954)",
"SILICIUMDIOXIDE (E 551)",
"SILICIUMDIOXIDE, GEHYDRATEERD (E 551)",
"TALK (E 553b)",
"TITAANDIOXIDE (E 171)"
],
"substances": [
"NATRIUMVALPROAAT",
"NATRIUMVALPROAAT",
"VALPROÏNEZUUR"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h33300.pdf",
"authorised_at": "2005/12/12",
"procedure_number": "NL/H/0736/002",
"dispensing_status": "Uitsluitend recept",
"registration_number": "33300",
"additional_monitoring": "Y"
}See everything about valproic acid.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.