United States· US:41520-264_65baf60d-f7f4-4482-a7a4-3aab220925e2
careone naproxen sodium pm
A naproxen and diphenhydramine product containing diphenhydramine hydrochloride; naproxen sodium, registered in United States by American Sales Company.
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- DIPHENHYDRAMINE HYDROCHLORIDE; NAPROXEN SODIUM
- Manufacturer
- American Sales Company
- Country
- United States (US)
- ATC code
- M01AE57
- ATC class
- Naproxen and diphenhydramine
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 27, 2026
Packs & prices · 4
- ndc1141520-264-27
- ndc1141520-264-60
- ndc1141520264271 BOTTLE in 1 CARTON (41520-264-27) / 80 TABLET, FILM COATED in 1 BOTTLE
- ndc1141520264601 BOTTLE in 1 CARTON (41520-264-60) / 20 TABLET, FILM COATED in 1 BOTTLE
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Naproxen and diphenhydramine in 1 other country
What each register calls a product with the same active substance — salts and hydrates count as the same.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/aecb8ee1-b628-45ab-84ff-3f51789cc08f GET /v1/drugs/aecb8ee1-b628-45ab-84ff-3f51789cc08f?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"route": "ORAL",
"source": "ndc",
"strength": "25; 220",
"substance": "DIPHENHYDRAMINE HYDROCHLORIDE; NAPROXEN SODIUM",
"productndc": "41520-264",
"dosage_form": "TABLET, FILM COATED",
"dea_schedule": null,
"strength_unit": "mg/1; mg/1",
"application_number": "ANDA208499",
"marketing_category": "ANDA"
}See everything about naproxen and diphenhydramine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.