Drug Database
Back to search

Netherlands· NL-82d84cfebbcc

Avtozma, 162 mg oplossing voor injectie in een voorgevulde spuit.

A tocilizumab product containing tocilizumab, registered in Netherlands by Celltrion Healthcare Hungary Kft.. The same ATC class is registered in 15 of our 19 countries.

ATC L04AC07

Checked against CBG-MEB (Netherlands) on

Informational only — not a medical device.

SOURCE REGISTER · NLCBG-MEB (Netherlands)normalisedAvtozma, 162 mg oplossing voor inject…ATCL04AC07REGISTER NO.NL-82d84cfebbccPACKS LISTED1CHECKEDSeptember 29, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about tocilizumabAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Tocilizumab is registered in 15 of 19 countries.

Countries holding a registration under ATC L04AC07 (tocilizumab), each read from that country’s own register.

  • This record: Netherlands, from CBG-MEB (Netherlands)
  • 9 of them publish a price we can compare per daily dose
Search tocilizumab products by name

Tocilizumab · ATC L04AC07

15 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Franceprice
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Sweden
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of tocilizumab costs, country by country.

Normalised to the WHO defined daily dose (20 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown
Open the full comparison — free accountDrug prices for market access

Tocilizumab · price per daily dose (20 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$29.63
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)
Active substance
TOCILIZUMAB
Manufacturer
Celltrion Healthcare Hungary Kft.
Country
Netherlands (NL)
ATC code
L04AC07
ATC class
Tocilizumab
Defined daily dose
20 mg, P
Reimbursed
Not published by this register
Source register
CBG-MEB (Netherlands)
Last checked
September 29, 2026

Packs & prices · 1

  • cbg_meb_id
    EU/1/24/1896

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

263 interactions on record for tocilizumab.

Graded by severity as the source publishes them — 38 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check tocilizumab against other medicinesHow interaction checks work

Tocilizumab · interactions on record

263 records

  • 38 severe
  • 218 moderate
  • 7 minor

Most severe, free to view

  • MipomersenC10AX11severe
  • LomitapideC10AX12severe
  • CladribineL01BB04severe
  • PexidartinibL01EX15severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Tocilizumab in 15 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All tocilizumab products

Authorised across Europe · EMA

The same active substance is authorised in 4 EEA countries. Names it is sold under:

  • United Kingdom (Northern Ireland) · Tofidence
  • Iceland · Avtozma, Roactemra
  • Liechtenstein · Avtozma, Roactemra
  • Norway · Avtozma, Roactemra

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/ae8f08ff-837f-462a-8cfa-7990359002ae
GET /v1/drugs/ae8f08ff-837f-462a-8cfa-7990359002ae?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Oplossing voor injectie",
  "route": "Subcutaan gebruik",
  "soort": null,
  "source": "cbg_meb",
  "smpc_url": "https://www.ema.europa.eu/en/documents/product-information/avtozma-epar-product-information_nl.pdf",
  "strength": null,
  "atc_label": "Tocilizumab",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp133010",
  "excipients": [
    "HISTIDINE, (L-)",
    "HISTIDINEMONOHYDROCHLORIDE 1-WATER (L-)",
    "METHIONINE, (L-)",
    "POLYSORBAAT 80 (E 433)",
    "THREONINE, (L-)",
    "WATER VOOR INJECTIE"
  ],
  "substances": [
    "TOCILIZUMAB"
  ],
  "leaflet_url": null,
  "authorised_at": "2025/02/14",
  "procedure_number": "EMEA/H/C/006196",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "EU/1/24/1896",
  "additional_monitoring": "Y"
}
API referenceMCP serverPlans

See everything about tocilizumab.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console