Netherlands· NL-8e5e840f2f6d

Atovaquon/Proguanil HCl CF 250/100 mg, filmomhulde tabletten

A proguanil and atovaquone product containing atovaquon + proguanilhydrochloride, registered in Netherlands by Centrafarm B.V.. The same ATC class is registered in 13 of our 19 countries.

ATC P01BB51

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about atovaquon + proguanilhydrochlorideAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Proguanil and atovaquone is registered in 13 of 19 countries.

Countries holding a registration under ATC P01BB51 (proguanil and atovaquone), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
8 of them publish a price we can compare per daily dose

Search proguanil and atovaquone products by name

Proguanil and atovaquone · ATC P01BB51

13 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of proguanil and atovaquone costs, country by country.

Normalised to the WHO defined daily dose (0.4 g), so markets compare like for like.

1 market with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Proguanil and atovaquone · price per daily dose (0.4 g)

USD · FX 28 Sept 2026

CH Switzerland$5.96

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: ATOVAQUON + PROGUANILHYDROCHLORIDE
Manufacturer: Centrafarm B.V.
Country: Netherlands (NL)
ATC code: P01BB51
ATC class: Proguanil and atovaquone
Defined daily dose: 0.4 g, Proguanilhydroch
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
118552

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

40 interactions on record for proguanil and atovaquone.

Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check proguanil and atovaquone against other medicines How interaction checks work

Proguanil and atovaquone · interactions on record

40 records

4 severe
27 moderate
3 minor

Most severe, free to view

EfavirenzJ05AG03severe
Sodium aurothiomalateM01CB01severe
AuranofinM01CB03severe
AurothioglucoseM01CB04severe

6 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Proguanil and atovaquone in 13 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All proguanil and atovaquone products

Authorised across Europe · EMA

The same active substance is authorised in 25 EEA countries. Names it is sold under:

Austria · Atovaquon/Proguanilhydrochlorid Glenmark, Atovaquon/Proguanilhydrochlorid Stada
Belgium · Atovaquone/Proguanil Eg, Atovaquone/Proguanil Viatris
Czechia · Malarone
Germany · Atovaquon/Proguanilhydrochlorid Al, Atovaquon/Proguanilhydrochlorid Amarox
Denmark · Atovaquon/Proguanilhydrochlorid Glenmark, Malarone
Estonia · Malarone, Malarone Paediatric
Spain · Atovacuona/Hidrocloruro De Proguanil Viatris, Malarone
Finland · Malarone
France · Atovaquone/Proguanil Bgr, Atovaquone/Proguanil Biogaran
United Kingdom (Northern Ireland) · Atovaquone/Proguanil Hydrochloride Amarox, Atovaquone/Proguanil Hydrochloride Glenmark Pharmaceuticals Eurpoe
Greece · Malarone
Hungary · Malarone
Ireland · Atovaquone/Proguanil Hydrochloride Glenmark Arzneimittel, Atovaquone/Proguanil Hydrochloride Viatris
Iceland · Malarone, Malastad
Italy · Atovaquone E Proguanile Mylan Generics, Malarone
Lithuania · Malarone
Luxembourg · Atovaquon/Proguanilhydrochlorid Ratiopharm, Atovaquone/Proguanil Eg
Latvia · Malarone
Malta · Atovaquone/Proguanil Hydrochloride Amarox, Malarone
Norway · Atovakon/Proguanil Glenmark, Malarone
Poland · Falcimar, Malarone
Portugal · Malarone
Sweden · Atovaquone / Proguanil Glenmark, Malarone Junior
Slovenia · Malarone
Slovakia · Malarone

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/adef1fe1-ad63-455c-96ec-57020af1aafa
GET /v1/drugs/adef1fe1-ad63-455c-96ec-57020af1aafa?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Filmomhulde tablet",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h118552_smpc.pdf",
  "strength": null,
  "atc_label": "Proguanil and atovaquone",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg118552",
  "excipients": [
    "CELLULOSE, MICROKRISTALLIJN (E 460(i))",
    "HYDROXYPROPYLCELLULOSE, LAAG GESUBSTITUEERD (E 463a)",
    "HYPROMELLOSE 2910 (3 - 15 mPa.s) (E 464)",
    "IJZEROXIDE ROOD  (E 172)",
    "MACROGOL 400",
    "MACROGOL 8000",
    "MAGNESIUMSTEARAAT (E 470b)",
    "NATRIUMZETMEELGLYCOLAAT",
    "POLOXAMEER 188",
    "POVIDON K 30 (E 1201)",
    "SILICIUMDIOXIDE (E 551)",
    "TITAANDIOXIDE (E 171)"
  ],
  "substances": [
    "ATOVAQUON",
    "PROGUANILHYDROCHLORIDE"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h118552.pdf",
  "authorised_at": "2016/12/13",
  "procedure_number": "NL/H/3931/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "118552",
  "additional_monitoring": "N"
}

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This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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