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United States· US:68682-938_9ec63a14-0b6a-47eb-9258-19b6e3cb5b25

Tolcapone

A tolcapone product containing tolcapone, registered in United States by Oceanside Pharmaceuticals. The same ATC class is registered in 15 of our 19 countries.

ATC N04BX01

Checked against FDA National Drug Code directory (United States) on

Informational only — not a medical device.

SOURCE REGISTER · USFDA National Drug Code directory (Unite…normalisedTolcaponeATCN04BX01REGISTER NO.US:68682-938_9ec63a14…PACKS LISTED2CHECKEDSeptember 27, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about tolcaponeAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Tolcapone is registered in 15 of 19 countries.

Countries holding a registration under ATC N04BX01 (tolcapone), each read from that country’s own register.

  • This record: United States, from FDA National Drug Code directory (United States)
  • 10 of them publish a price we can compare per daily dose
Search tolcapone products by name

Tolcapone · ATC N04BX01

15 / 19 countries

  • Belgiumprice
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Franceprice
  • Germany
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of tolcapone costs, country by country.

Normalised to the WHO defined daily dose (0.45 g), the median price runs from $6.12 in France to $9.92 in Switzerland — a ×1.6 gap.

  • 3 markets with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown
Open the full comparison — free accountDrug prices for market access

Tolcapone · price per daily dose (0.45 g)

USD · FX 28 Sept 2026

  • CH Switzerland$9.92
  • IT Italy$8.47
  • FR France$6.12
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)
Active substance
TOLCAPONE
Manufacturer
Oceanside Pharmaceuticals
Country
United States (US)
ATC code
N04BX01
ATC class
Tolcapone
Defined daily dose
0.45 g, O
Reimbursed
Not published by this register
Source register
FDA National Drug Code directory (United States)
Last checked
September 27, 2026

Packs & prices · 2

  • ndc11
    68682-938-90
  • ndc11
    6868293890
    90 TABLET, FILM COATED in 1 BOTTLE (68682-938-90)

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

88 interactions on record for tolcapone.

Graded by severity as the source publishes them — 6 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check tolcapone against other medicinesHow interaction checks work

Tolcapone · interactions on record

88 records

  • 6 severe
  • 74 moderate
  • 2 minor
  • 6 info

Most severe, free to view

  • ProcarbazineL01XB01severe
  • LeflunomidL04AA13severe
  • TeriflunomidL04AA31severe
  • LeflunomideL04AK01severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Tolcapone in 15 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All tolcapone products

Authorised across Europe · EMA

The same active substance is authorised in 4 EEA countries. Names it is sold under:

  • Germany · Tolcapon Neuraxpharm
  • Iceland · Tasmar
  • Liechtenstein · Tasmar
  • Norway · Tasmar

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/ad4bc2f6-cfbb-44ec-aedf-4b617c09f5a6
GET /v1/drugs/ad4bc2f6-cfbb-44ec-aedf-4b617c09f5a6?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "route": "ORAL",
  "source": "ndc",
  "strength": "100",
  "substance": "TOLCAPONE",
  "productndc": "68682-938",
  "dosage_form": "TABLET, FILM COATED",
  "dea_schedule": null,
  "strength_unit": "mg/1",
  "application_number": "NDA020697",
  "marketing_category": "NDA AUTHORIZED GENERIC"
}
API referenceMCP serverPlans

See everything about tolcapone.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console