France· FR:62258872
ZORYON 20 mg/15 ml, sirop en récipient unidose
A methadone product containing chlorhydrate de méthadone, registered in France by ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS - AP-HP, on the national reimbursement list. The same ATC class is registered in 17 of our 19 countries.
Checked against Base de données publique des médicaments — BDPM (France) on
Informational only — not a medical device.
Where it is registered
Methadone is registered in 17 of 19 countries.
Countries holding a registration under ATC N07BC02 (methadone), each read from that country’s own register.
- This record: France, from Base de données publique des médicaments — BDPM (France)
- 9 of them publish a price we can compare per daily dose
Methadone · ATC N07BC02
17 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of methadone costs, country by country.
Normalised to the WHO defined daily dose (25 mg), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Methadone · price per daily dose (25 mg)
USD · FX 28 Sept 2026
- CH Switzerland$0.81
The record
At a glance
Base de données publique des médicaments — BDPM (France)- Active substance
- CHLORHYDRATE DE MÉTHADONE
- Manufacturer
- ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS - AP-HP
- Country
- France (FR)
- ATC code
- N07BC02
- ATC class
- Methadone
- Defined daily dose
- 25 mg, O
- Reimbursed
- Yes
- Source register
- Base de données publique des médicaments — BDPM (France)
- Last checked
- September 12, 2026
Packs & prices · 1
1 priced- cip1334009301679601 flacon en verre brun unidose avec fermeture de sécurité enfantEUR 1.51
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
433 interactions on record for methadone.
Graded by severity as the source publishes them — 153 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Methadone · interactions on record
433 records
- 153 severe
- 176 moderate
- 5 minor
- 36 info
Most severe, free to view
- PapaverineA03AD01severe
- CisaprideA03FA02severe
- OndansetronA04AA01severe
- GranisetronA04AA02severe
63 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Methadone in 17 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomEptadone 1mg/ml oral solutionDee Pharmaceuticals Ltd
- NorwayMetadon AbcurAbcur AB
- United StatesDISKETSHikma Pharmaceuticals USA Inc.
- SwitzerlandKetalgin
- SwedenMetadon 2care4 10 mg Tablett2care4 Generics ApS
- FinlandDolmedOrifarm Healthcare A/S
- NetherlandsEptadone Drank Suikervrij 10 mg/mlL. Molteni & C. Dei Fratelli Alitti Societa Di Esercizio S.p.A.
- CanadaAPO-METHADONEAPOTEX INC
Authorised across Europe · EMA
The same active substance is authorised in 27 EEA countries. Names it is sold under:
- Austria · Methadon G.L., Methasan
- Belgium · Mephenon
- Bulgaria · Метадон Алкалоид, Метадон Софарма
- Czechia · Misyo, Sublana
- Germany · Methaddict, Methadon G.L. Pharma
- Denmark · Marlodon, Metadon
- Estonia · Metadon Dak
- Spain · Eptadone, Metasedin
- Finland · Dolmed, Metadon
- United Kingdom (Northern Ireland) · Methadone, Methadone Accord Healthcare
- Greece · Methadone Ι.Φ.Ε.Τ.
- Croatia · Heptanon, Metadon Alkaloid
- Hungary · Metadon, Metadon Ep
- Ireland · Methadone Hydrochloride Alkaloid-Int, Methadone Hydrochloride Ascot Laboratories (Ireland)
- Iceland · Metadon 2care4, Metadon Abcur
- Italy · Eptadone, Metadone Cloridrato Molteni
- Lithuania · Metadon Dak
- Luxembourg · Mephenon, Methasan
- Malta · Methadone Alkaloid, Pinadone
- Netherlands · Eptadone Suikervrij, Methadon Hci Sandoz
- Norway · Metadon Abcur, Metadon Dne
- Poland · Methadone Hydrochloride Inn-Farm, Methadone Hydrochloride Molteni
- Portugal · Misyo
- Romania · Metadon Bioeel, Methasan
- Sweden · Metadon, Metadon Abcur
- Slovenia · Metadonijev Klorid Alkaloid-Int
- Slovakia · Metagla, Misyo
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Base de données publique des médicaments — BDPM (France). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ad42eb7b-9fc8-4fc1-95ad-81ea93559551 GET /v1/drugs/ad42eb7b-9fc8-4fc1-95ad-81ea93559551?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"cis": "62258872",
"date_amm": "2018-12-27",
"type_amm": "Procédure nationale",
"numero_ue": null,
"substance": "CHLORHYDRATE DE MÉTHADONE",
"atc_source": "fr_atc_restore_2026-09-06",
"statut_amm": "Autorisation active",
"statut_bdm": "Warning disponibilité",
"forme_pharmaceutique": "sirop",
"voies_administration": "orale",
"etat_commercialisation": "Non commercialisée",
"surveillance_renforcee": "Non"
}See everything about methadone.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.