United States· US:43547-288_e8f3396b-251b-4218-9dd8-4ad0a0f8f2a2
bupropion hydrochloride
A bupropion product containing bupropion hydrochloride, registered in United States by Solco Healthcare US LLC. The same ATC class is registered in 13 of our 19 countries.
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
Where it is registered
Bupropion is registered in 13 of 19 countries.
Countries holding a registration under ATC N06AX12 (bupropion), each read from that country’s own register.
- This record: United States, from FDA National Drug Code directory (United States)
- 9 of them publish a price we can compare per daily dose
Bupropion · ATC N06AX12
13 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Statesprice
Price per daily dose
What a daily dose of bupropion costs, country by country.
Normalised to the WHO defined daily dose (0.15 g), the median price runs from $0.10 in United States to $1.25 in Switzerland — a ×12 gap.
- United States: $0.10 per daily dose (median across products in the class)
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Bupropion · price per daily dose (0.15 g)
USD · FX 28 Sept 2026
- CH Switzerland$1.25
- IT Italy$0.90
- US United States$0.10 (acquisition cost)
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- Bupropion hydrochloride
- Manufacturer
- Solco Healthcare US LLC
- Country
- United States (US)
- ATC code
- N06AX12
- ATC class
- Bupropion
- Defined daily dose
- 0.15 g, O
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 12, 2026
Packs & prices · 4
- ndc11435472880660 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (43547-288-06)
- ndc11435472880990 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (43547-288-09)
- ndc114354728810100 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (43547-288-10)
- ndc114354728850500 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (43547-288-50)
Regulatory notes
Interactions
808 interactions on record for bupropion.
Graded by severity as the source publishes them — 230 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Bupropion · interactions on record
808 records
- 230 severe
- 217 moderate
- 4 minor
- 316 info
Most severe, free to view
- MetoclopramideA03FA01severe
- OndansetronA04AA01severe
- GranisetronA04AA02severe
- DolasetronA04AA04severe
41 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Bupropion in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- PolandBucidarRanbaxy (Poland) Sp. z o.o.
- CzechiaBUPROPION +PHARMA+pharma arzneimittel gmbh, Graz
- SwedenBupropion Accord 150 mg Tablett med modifierad frisättningAccord Healthcare B.V.
- NetherlandsBupropion HCL 150 mg Focus Care, tabletten met gereguleerde afgifteFocus Care Pharmaceuticals B.V.
- SpainBUPROPION ACCORD 150 MG COMPRIMIDOS DE LIBERACION MODIFICADA EFGAccord Healthcare S.L.U.
- FinlandBupropion AccordAccord Healthcare B.V.
- GermanyBupropionBetapharm Arzneimittel Gmbh
- BelgiumBupropion EG 300 mgEG
Authorised across Europe · EMA
The same active substance is authorised in 29 EEA countries. Names it is sold under:
- Austria · Bupropion !$tada, Bupropion +pharma
- Belgium · Bupropion Eg, Bupropion Sandoz
- Cyprus · Wellbutrin Xr
- Czechia · Bupropion +pharma, Bupropion Neuraxpharm
- Germany · Bupropion, Bupropion 1 A Pharma
- Denmark · Bupropion Hydrochloride Zentiva, Bupropionhydrochlorid Stada
- Estonia · Elontril
- Spain · Bupropion Accord, Bupropión Cinfa
- Finland · Bupropion Accord, Bupropion Omet Pharma
- France · Zyban L.P.
- United Kingdom (Northern Ireland) · Zyban
- Greece · Wellbutrin Xr
- Croatia · Bupropion Genericon, Wellbutrin Xr
- Hungary · Elontril
- Ireland · Zyban
- Iceland · Bupropion Teva, Wellbutrin Retard
- Italy · Bupropion Sun, Bupropione Doc
- Lithuania · Elontril
- Luxembourg · Bupropion Eg, Bupropion Ratiopharm
- Latvia · Wellbutrin Sr
- Malta · Bupropion Generis, Wellbutrin Xr
- Netherlands · Bupropion Hcl 1a Retard 1a Pharma, Bupropion Hcl Accord
- Norway · Bupropion Hydrochloride Teva, Bupropion Hydrochloride Zentiva
- Poland · Bucidar, Bupropion
- Portugal · Bupropiom Generis, Bupropiom Ratiopharm
- Romania · Axabal, Elontril
- Sweden · Bupropion Accord, Bupropion Bluefish
- Slovenia · Bupropion Accord, Wellbutrin Xr
- Slovakia · Bupropion Neuraxpharm, Elontril
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ace098fb-85b1-4a9b-a5d7-6a51c3f0a079 GET /v1/drugs/ace098fb-85b1-4a9b-a5d7-6a51c3f0a079?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"unii": {
"unii": "ZG7E5POY8O",
"rxcui": "203204",
"inchikey": "HEYVINCGKDONRU-UHFFFAOYSA-N",
"display_name": "BUPROPION HYDROCHLORIDE",
"substance_type": "chemical",
"ingredient_type": "INGREDIENT SUBSTANCE"
},
"route": "ORAL",
"livertox": {
"summary": null,
"livertox_id": null,
"hepatotoxicity_score": 3
},
"spl_meta": {
"cefaaa17-f79a-4ba6-8f97-a59f60e07b75": {
"match": "brand_token",
"title": "BUPROPION HYDROCHLORIDE (XL) (BUPROPION HYDROCHLORIDE) TABLET, FILM COATED, EXTENDED RELEASE [BRYANT RANCH PREPACK]",
"spl_version": "105",
"published_date": "2026-06-01"
}
},
"productid": "43547-288_e8f3396b-251b-4218-9dd8-4ad0a0f8f2a2",
"productndc": "43547-288",
"dosage_form": "TABLET, FILM COATED, EXTENDED RELEASE",
"orange_book": {
"appl_no": "202304",
"products": [
{
"rs": false,
"rld": false,
"te_code": "AB1",
"strength": "100MG",
"product_no": "001",
"approval_date": "May 26, 2015"
},
{
"rs": false,
"rld": false,
"te_code": "AB1",
"strength": "150MG",
"product_no": "002",
"approval_date": "May 26, 2015"
},
{
"rs": false,
"rld": false,
"te_code": "AB1",
"strength": "200MG",
"product_no": "003",
"approval_date": "May 26, 2015"
}
],
"appl_type": "A"
},
"dea_schedule": null,
"product_type": "HUMAN PRESCRIPTION DRUG",
"substance_name": "BUPROPION HYDROCHLORIDE",
"proprietary_name": "bupropion hydrochloride",
"active_ingred_unit": "mg/1",
"application_number": "ANDA202304",
"marketing_category": "ANDA",
"nonproprietary_name": "Bupropion hydrochloride",
"start_marketing_date": "20141101",
"active_numerator_strength": "100"
}See everything about bupropion.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.