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Japan· JP-2129006F1050

プロパフェノン塩酸塩

A propafenone product containing プロパフェノン塩酸塩, registered in Japan by 大原薬品工業, on the national reimbursement list. The same ATC class is registered in 16 of our 19 countries.

On Japan’s NHI price listATC C01BC03

Checked against MHLW / PMDA (Japan) on

Informational only — not a medical device.

SOURCE REGISTER · JPMHLW / PMDA (Japan)normalisedプロパフェノン塩酸塩ATCC01BC03REGISTER NO.JP-2129006F1050PACKS LISTED0CHECKEDSeptember 25, 2026

Where it is registered

Propafenone is registered in 16 of 19 countries.

Countries holding a registration under ATC C01BC03 (propafenone), each read from that country’s own register.

  • This record: Japan, from MHLW / PMDA (Japan)
  • 9 of them publish a price we can compare per daily dose

Propafenone · ATC C01BC03

16 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Franceprice
  • Germany
  • Ireland
  • Italyprice
  • Japan
  • Netherlands
  • Norwayprice
  • Polandprice
  • Spainprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of propafenone costs, country by country.

Normalised to the WHO defined daily dose (0.5 g), the median price runs from $0.23 in France to $0.68 in United States — a ×2.9 gap.

  • 4 markets with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown
  • US figures are pharmacy acquisition cost (CMS NADAC), not retail

Propafenone · price per daily dose (0.5 g)

USD · FX 28 Sept 2026

  • US United States$0.68 (acquisition cost)
  • IT Italy$0.45
  • ES Spain$0.28
  • FR France$0.23
Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

MHLW / PMDA (Japan)
Active substance
プロパフェノン塩酸塩
Manufacturer
大原薬品工業
Country
Japan (JP)
ATC code
C01BC03
ATC class
Propafenone
Defined daily dose
0.5 g, O
Reimbursed
Yes
Source register
MHLW / PMDA (Japan)
Last checked
September 25, 2026

Packs & prices · 0

No packs listed by the register for this record.

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

311 interactions on record for propafenone.

Graded by severity as the source publishes them — 47 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Propafenone · interactions on record

311 records

  • 47 severe
  • 192 moderate
  • 7 minor
  • 19 info

Most severe, free to view

  • PapaverineA03AD01severe
  • CisaprideA03FA02severe
  • DolasetronA04AA04severe
  • EliglustatA16AX10severe

46 more interactions with mechanism and management, from a commercially licensed source.

Sign in to check
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of MHLW / PMDA (Japan). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/ab445f95-198e-48c0-b1ce-b5faf6ee1239
GET /v1/drugs/ab445f95-198e-48c0-b1ce-b5faf6ee1239?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "spec": "150mg1錠",
  "marks": "局",
  "source": "mhlw",
  "remarks": null,
  "yj_code": "2129006F1050",
  "category": "内用薬",
  "price_yen": 12.8,
  "generic_name": "プロパフェノン塩酸塩",
  "product_name_jp": null,
  "therapeutic_class": "2129",
  "transitional_expiry": null
}

See everything about propafenone.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.