Netherlands· NL-0e38636d6469
Kruidvat Ibuprofen bruis 400 mg, bruisgranulaat
A ibuprofen product containing ibuprofen, registered in Netherlands by MAE Holding B.V.. The same ATC class is registered in 12 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Ibuprofen is registered in 12 of 19 countries.
Countries holding a registration under ATC M01AE01 (ibuprofen), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 8 of them publish a price we can compare per daily dose
Ibuprofen · ATC M01AE01
12 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
Price per daily dose
What a daily dose of ibuprofen costs, country by country.
Normalised to the WHO defined daily dose (1.2 g), the median price runs from $0.28 in Italy to $1.24 in Switzerland — a ×4.4 gap.
- 2 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Ibuprofen · price per daily dose (1.2 g)
USD · FX 28 Sept 2026
- CH Switzerland$1.24
- IT Italy$0.28
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- IBUPROFEN
- Manufacturer
- MAE Holding B.V.
- Country
- Netherlands (NL)
- ATC code
- M01AE01
- ATC class
- Ibuprofen
- Defined daily dose
- 1.2 g, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id113861
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
886 interactions on record for ibuprofen.
Graded by severity as the source publishes them — 71 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Ibuprofen · interactions on record
886 records
- 71 severe
- 306 moderate
- 15 minor
- 413 info
Most severe, free to view
- DicoumarolB01AA01severe
- WarfarinB01AA03severe
- DalteparinB01AB04severe
- EnoxaparinB01AB05severe
81 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Ibuprofen in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- SwitzerlandSpedifen 400, granulareZambon Svizzera SA
- FinlandBrufenAbbott Oy
- United States365 whole foods market ibuprofenWhole Foods Market, INC.
- CzechiaAPO-IBUPROFEN RAPIDPatheon Softgels B.V., Tilburg
- United KingdomAdvil 200mg tabletsWyeth Consumer Healthcare
- SpainALGIDRIN 600 POLVO PARA SUSPENSION ORALLaboratorio De Aplicaciones Farmacodinamicas S.A.
- PolandAxoprofenAristo Pharma Sp. z o.o.
- GermanyAktren ForteBayer Vital Gmbh
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Adolorin Ibuforte Direkt, Adolorini Direkt
- Belgium · Brufen, Brufen Forte
- Bulgaria · Ibuprofen Nutra Essential, Ibuprofen Pharmdedict
- Cyprus · Algovil, Algovil Rapid
- Czechia · Brufen, Brufen Rapidcaps
- Germany · Aktren Forte, Ambaprofen
- Denmark · Brufen, Brufen Retard
- Estonia · Brufen, Dolgit
- Spain · Apirofeno, Aragel
- Finland · Burana, Burana Mustaherukka
- France · Advil, Advilcaps
- United Kingdom (Northern Ireland) · 3 Months Ibuprofen Strawberry Flavour, 3 Months Plus Strawberry Flavour
- Greece · Advil, Advil Forte
- Croatia · Blokmax, Blokmax Forte
- Hungary · Advil Ultra, Advil Ultra Forte
- Ireland · Actiprofen, Advil Liquid
- Iceland · Alvofen Express, Alvofen Junior
- Italy · Algofen, Algopirina Febbre E Dolore Bambini Gusto Arancia Senza Zucchero
- Liechtenstein · Ibuprofen Gen.Orph, Pedea
- Lithuania · Brufen, Deliprom
- Luxembourg · Brufen, Brufen Forte
- Latvia · Brufen, Ibugard
- Malta · Algofren, Brufen
- Norway · Brufen Retard, Ibumax
- Poland · Axoprofen, Axoprofen Forte
- Portugal · Algik, Azevedos
- Romania · Adagin, Adagin Forte
- Sweden · Brufen, Brufen Retard
- Slovenia · Brufen, Brufen Retard
- Slovakia · Brufen, Brufen Instant
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/aaa8a8a9-0c38-4417-bc54-2b61cf8e810c GET /v1/drugs/aaa8a8a9-0c38-4417-bc54-2b61cf8e810c?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Bruisgranulaat",
"route": "Oraal gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h113861_smpc.pdf",
"strength": null,
"atc_label": "Ibuprofen",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg113861",
"excipients": [
"ARABISCHE GOM (E 414)",
"BUTYLHYDROXYANISOL (E 320)",
"CITROENZUUR 0-WATER (E 330)",
"CITROENZUUR 0-WATER (E 330)",
"GLUCOSE 1-WATER",
"LACTOSE 0-WATER",
"MALTODEXTRINE",
"NATRIUMCARBONAAT 0-WATER (E 500 (I))",
"NATRIUMLAURILSULFAAT",
"NATRIUMWATERSTOFCARBONAAT (E 500 (II))",
"POVIDON K 25 (E 1201)",
"SACCHAROIDE NATRIUM X-WATER (E 954)",
"SILICIUMDIOXIDE (E 551)",
"SINAASAPPELSMAAKSTOF"
],
"substances": [
"IBUPROFEN"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h113861.pdf",
"authorised_at": "2014/11/18",
"procedure_number": null,
"dispensing_status": "Uitsluitend apotheek$SEMICOLON$ Uitsluitend apotheek of drogist - UA meer dan 24 eenheden - UAD maximaal 24 eenheden",
"registration_number": "113861",
"additional_monitoring": "N"
}See everything about ibuprofen.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.