Netherlands· NL-7d0a5e28a20d
Lonsurf 15 mg, filmomhulde tabletten
A trifluridin, kombinationen product containing tipiracilhydrochloride + trifluridine, registered in Netherlands by Taiho Pharma Europe Ltd.. The same ATC class is registered in 11 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Trifluridin, kombinationen is registered in 11 of 19 countries.
Countries holding a registration under ATC L01BC59 (trifluridin, kombinationen), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 7 of them publish a price we can compare per daily dose
Trifluridin, kombinationen · ATC L01BC59
11 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
Price per daily dose
What a daily dose of trifluridin, kombinationen costs, country by country.
Normalised to the WHO defined daily dose (45 mg), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Trifluridin, kombinationen · price per daily dose (45 mg)
USD · FX 28 Sept 2026
- CH Switzerland$126.56
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- TIPIRACILHYDROCHLORIDE + TRIFLURIDINE
- Manufacturer
- Taiho Pharma Europe Ltd.
- Country
- Netherlands (NL)
- ATC code
- L01BC59
- ATC class
- Trifluridin, Kombinationen
- Defined daily dose
- 45 mg, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_idEU/1/16/1096
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
72 interactions on record for trifluridin, kombinationen.
Graded by severity as the source publishes them — 29 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Trifluridin, kombinationen · interactions on record
72 records
- 29 severe
- 43 moderate
Most severe, free to view
- CladribineL01BB04severe
- Talimogene laherparepvecL01XL02severe
- Talimogen laherparepvecL01XX51severe
- LeflunomidL04AA13severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Trifluridin, kombinationen in 12 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- SpainLONSURF 15 MG/6,14 MG COMPRIMIDOS RECUBIERTOS CON PELICULALes Laboratoires Servier
- CzechiaLONSURFLes Laboratoires Servier, Suresnes cedex
- SwitzerlandLonsurf 15 mg/6.14 mg, comprimés pelliculésServier (Suisse) SA
- FinlandLonsurfLes Laboratoires Servier
- PolandLonsurfLes Laboratoires Servier
- SwedenLonsurf 15 mg/ 6,14 mg Filmdragerad tablettLes Laboratoires Servier
- CanadaLONSURFTAIHO PHARMA CANADA, INC.
- United StatesLONSURFTaiho Pharmaceutical Co., Ltd.
Authorised across Europe · EMA
The same active substance is authorised in 7 EEA countries. Names it is sold under:
- Belgium · Trifluridine/Tipiracil Eugia
- Spain · Trifluridina/Tipiracilo Eugia
- Iceland · Lonsurf
- Liechtenstein · Lonsurf
- Luxembourg · Trifluridine/Tipiracil Eugia
- Norway · Lonsurf
- Portugal · Trifluridina + Tipiracilo Eugia
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/a486169a-6da3-4a99-b872-5f1a2b1beadf GET /v1/drugs/a486169a-6da3-4a99-b872-5f1a2b1beadf?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Filmomhulde tablet",
"route": "Oraal gebruik",
"soort": null,
"source": "cbg_meb",
"smpc_url": "https://www.ema.europa.eu/en/documents/product-information/lonsurf-epar-product-information_nl.pdf",
"strength": null,
"atc_label": "Trifluridine, combinations",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp117070",
"excipients": [
"CARNAUBAWAS (E 903)",
"GRIJZE INKT",
"HYPROMELLOSE 2910 (3 - 15 mPa.s) (E 464)",
"IJZEROXIDE GEEL (E 172)",
"IJZEROXIDE ROOD (E 172)",
"IJZEROXIDE ROOD (E 172)",
"INDIGOKARMIJN ALUMINIUMLAK (E 132)",
"LACTOSE 1-WATER",
"MACROGOL 8000",
"MAGNESIUMSTEARAAT (E 470b)",
"MAÏSZETMEEL, GEPREGELATINEERD",
"SCHELLAK (E 904)",
"STEARINEZUUR (E 570)",
"TALK (E 553b)",
"TITAANDIOXIDE (E 171)",
"TITAANDIOXIDE (E 171)"
],
"substances": [
"TIPIRACILHYDROCHLORIDE",
"TRIFLURIDINE"
],
"leaflet_url": null,
"authorised_at": "2016/04/25",
"procedure_number": "EMEA/H/C/003897",
"dispensing_status": "Uitsluitend recept",
"registration_number": "EU/1/16/1096",
"additional_monitoring": "N"
}See everything about trifluridin, kombinationen.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.