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Netherlands· NL-dd4440e231e6

Provocholine 100 mg poeder voor verneveloplossing

A methacholine product containing methacholine chloride, registered in Netherlands by Methapharm Limited. The same ATC class is registered in 8 of our 19 countries.

ATC V04CX03

Checked against CBG-MEB (Netherlands) on

Informational only — not a medical device.

SOURCE REGISTER · NLCBG-MEB (Netherlands)normalisedProvocholine 100 mg poeder voor verne…ATCV04CX03REGISTER NO.NL-dd4440e231e6PACKS LISTED1CHECKEDSeptember 29, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about methacholine chlorideAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Methacholine is registered in 8 of 19 countries.

Countries holding a registration under ATC V04CX03 (methacholine), each read from that country’s own register.

  • This record: Netherlands, from CBG-MEB (Netherlands)
  • 2 of them publish a price we can compare per daily dose
Search methacholine products by name

Methacholine · ATC V04CX03

8 / 19 countries

  • Denmark
  • Germany
  • Ireland
  • Japan
  • Netherlands
  • Norwayprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)
Active substance
METHACHOLINE CHLORIDE
Manufacturer
Methapharm Limited
Country
Netherlands (NL)
ATC code
V04CX03
ATC class
Methacholine
Reimbursed
Not published by this register
Source register
CBG-MEB (Netherlands)
Last checked
September 29, 2026

Packs & prices · 1

  • cbg_meb_id
    123652

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

24 interactions on record for methacholine.

Graded by severity as the source publishes them — 18 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check methacholine against other medicinesHow interaction checks work

Methacholine · interactions on record

24 records

  • 18 severe
  • 6 moderate

Most severe, free to view

  • PindololC07AA03severe
  • PropranololC07AA05severe
  • TimololC07AA06severe
  • SotalolC07AA07severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Methacholine in 10 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All methacholine products

Authorised across Europe · EMA

The same active substance is authorised in 8 EEA countries. Names it is sold under:

  • Germany · Provokit
  • Denmark · Provocholine
  • Spain · Provocholine
  • France · Chlorure De Methacholine Panpharma
  • Ireland · Methacholine Chloride Methapharm
  • Italy · Metacolina Lofarma
  • Norway · Provocholine
  • Sweden · Provocholine

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/a096a8ca-817b-41b4-823d-7b33241a7aa9
GET /v1/drugs/a096a8ca-817b-41b4-823d-7b33241a7aa9?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Poeder voor verneveloplossing",
  "route": "Inhalatie",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h123652_smpc.pdf",
  "strength": null,
  "atc_label": "Methacholine",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg123652",
  "excipients": [
    "STIKSTOF (HEAD SPACE) (E 941)"
  ],
  "substances": [
    "METHACHOLINE CHLORIDE"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h123652.pdf",
  "authorised_at": "2020/06/17",
  "procedure_number": "DK/H/2952/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "123652",
  "additional_monitoring": "N"
}
API referenceMCP serverPlans

See everything about methacholine.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console