Czechia· CZ-0191651
PROGRAF
A tacrolimus product containing tacrolimus monohydrate, registered in Czechia by Astellas Pharma s.r.o., Praha. The same ATC class is registered in 16 of our 19 countries.
Checked against SÚKL (Czech Republic) on
Informational only — not a medical device.
Where it is registered
Tacrolimus is registered in 16 of 19 countries.
Countries holding a registration under ATC L04AD02 (tacrolimus), each read from that country’s own register.
- This record: Czechia, from SÚKL (Czech Republic)
- 9 of them publish a price we can compare per daily dose
Tacrolimus · ATC L04AD02
16 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of tacrolimus costs, country by country.
Normalised to the WHO defined daily dose (5 mg), the median price runs from $0.77 in United States to $15.16 in Switzerland — a ×20 gap.
- 4 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Tacrolimus · price per daily dose (5 mg)
USD · FX 28 Sept 2026
- CH Switzerland$15.16
- IT Italy$8.99
- ES Spain$6.82
- US United States$0.77 (acquisition cost)
The record
At a glance
SÚKL (Czech Republic)- Active substance
- TACROLIMUS MONOHYDRATE
- Manufacturer
- Astellas Pharma s.r.o., Praha
- Country
- Czechia (CZ)
- ATC code
- L04AD02
- ATC class
- Tacrolimus
- Defined daily dose
- 5 mg, O
- Reimbursed
- Not published by this register
- Source register
- SÚKL (Czech Republic)
- Last checked
- September 28, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
1075 interactions on record for tacrolimus.
Graded by severity as the source publishes them — 238 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Tacrolimus · interactions on record
1075 records
- 238 severe
- 543 moderate
- 18 minor
- 217 info
Most severe, free to view
- ClotrimazoleA01AB18severe
- OmeprazoleA02BC01severe
- LansoprazoleA02BC03severe
- EsomeprazoleA02BC05severe
59 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Tacrolimus in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatestacrolimusGlenmark Pharmaceuticals Inc., USA
- NetherlandsAdport 5 mg, capsules, hardSandoz B.V.
- FinlandAdportSandoz A/S
- United KingdomAdoport 5mg capsulesSandoz Ltd
- SwedenAdoport 5 mg Kapsel, hårdMedartuum AB
- SwitzerlandAdvagraf
- SpainADOPORT 5 mg CAPSULAS DURAS EFGSandoz Farmaceutica S.A.
- BelgiumAdoport 5 mgSandoz
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Adport, Dailiport
- Belgium · Adoport, Dailiport
- Bulgaria · Програф
- Cyprus · Prograf, Tacrolimus Accord
- Germany · Crilomus, Dailiport
- Denmark · Adport, Dailiport
- Estonia · Dailiport, Lebsanan
- Spain · Adoport, Cellmune
- Finland · Adport, Adport,
- France · Adoport, Conferoport
- United Kingdom (Northern Ireland) · Adoport, Ascezo
- Greece · Atodrit-Dermo, Eczatope Derm
- Croatia · Atezyrix, Dermitopic
- Hungary · Prograf, Tacrolimus Stada
- Ireland · Prograf, Tacrolimus Accord
- Iceland · Advagraf, Dailiport
- Italy · Adoport, Carelimus
- Liechtenstein · Advagraf, Envarsus
- Lithuania · Dailiport, Lebsanan
- Luxembourg · Prograft, Sumilor
- Latvia · Dailiport, Lebsanan
- Malta · Prograf
- Netherlands · Adport, Conferoport
- Norway · Adport, Advagraf
- Poland · Cidimus, Dailiport
- Portugal · Adoport, Dermitopic
- Romania · Prograf, Tacrolimus Sandoz
- Sweden · Adport, Adport,
- Slovenia · Adoport, Dailiport
- Slovakia · Atezyrix, Dailiport
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of SÚKL (Czech Republic). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/99f0be8e-db97-4a2d-814f-351831813ab7 GET /v1/drugs/99f0be8e-db97-4a2d-814f-351831813ab7?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "CPS DUR",
"source": "sukl",
"strength": "5MG",
"pack_size": "50X1",
"substance": "TACROLIMUS MONOHYDRATE",
"cz_kod_sukl": "0191651",
"product_type": "CH",
"substance_codes": "16808",
"registration_state": "R",
"registration_number": "59/759/99-C"
}See everything about tacrolimus.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.