United States· US:0023-4491_74f3d119-623c-4bd1-a5aa-e92db774f116
REFRESH OPTIVE Advanced
A medicinal product containing carboxymethylcellulose sodium; glycerin; polysorbate 80, registered in United States by Allergan, Inc..
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- CARBOXYMETHYLCELLULOSE SODIUM; GLYCERIN; POLYSORBATE 80
- Manufacturer
- Allergan, Inc.
- Country
- United States (US)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 27, 2026
Packs & prices · 4
- ndc1100234491055 VIAL, SINGLE-USE in 1 CARTON (0023-4491-05) / .4 mL in 1 VIAL, SINGLE-USE
- ndc11002344913030 VIAL, SINGLE-USE in 1 CARTON (0023-4491-30) / .4 mL in 1 VIAL, SINGLE-USE
- ndc110023-4491-05
- ndc110023-4491-30
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Carboxymethylcellulose sodium; glycerin; polysorbate 80 in 1 other country
What each register calls a product with the same active substance — salts and hydrates count as the same.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/987223f5-099f-41e1-b22d-090378d7beb1 GET /v1/drugs/987223f5-099f-41e1-b22d-090378d7beb1?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"route": "OPHTHALMIC",
"source": "ndc",
"strength": "5; 10; 5",
"substance": "CARBOXYMETHYLCELLULOSE SODIUM; GLYCERIN; POLYSORBATE 80",
"productndc": "0023-4491",
"dosage_form": "SOLUTION/ DROPS",
"dea_schedule": null,
"strength_unit": "mg/mL; mg/mL; mg/mL",
"application_number": "M018",
"marketing_category": "OTC MONOGRAPH DRUG"
}See everything about carboxymethylcellulose sodium; glycerin; polysorbate 80.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.