Netherlands· NL-6fe6a675c3bc
Daraprim 25 mg tabletten
A pyrimethamine product containing pyrimethamine, registered in Netherlands by GlaxoSmithKline B.V.. The same ATC class is registered in 9 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Pyrimethamine is registered in 9 of 19 countries.
Countries holding a registration under ATC P01BD01 (pyrimethamine), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 6 of them publish a price we can compare per daily dose
Pyrimethamine · ATC P01BD01
9 / 19 countries
- Belgiumprice
- Finlandprice
- Franceprice
- Germany
- Netherlands
- Norwayprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of pyrimethamine costs, country by country.
Normalised to the WHO defined daily dose (75 mg), the median price runs from $0.97 in France to $3.75 in Switzerland — a ×3.9 gap.
- 2 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Pyrimethamine · price per daily dose (75 mg)
USD · FX 28 Sept 2026
- CH Switzerland$3.75
- FR France$0.97
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- PYRIMETHAMINE
- Manufacturer
- GlaxoSmithKline B.V.
- Country
- Netherlands (NL)
- ATC code
- P01BD01
- ATC class
- Pyrimethamine
- Defined daily dose
- 75 mg, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id00254
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
48 interactions on record for pyrimethamine.
Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Pyrimethamine · interactions on record
48 records
- 4 severe
- 28 moderate
- 2 minor
- 14 info
Most severe, free to view
- Sodium aurothiomalateM01CB01severe
- AuranofinM01CB03severe
- AurothioglucoseM01CB04severe
- DeferiproneV03AC02severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Pyrimethamine in 8 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesDaraprimVyera Pharmaceuticals LLC
- SwitzerlandDaraprim
- SpainDARAPRIM 25 mg COMPRIMIDOSSmithkline Beecham Farma S.A.
- United KingdomDaraprim 25mg tabletsGlaxoSmithKline UK Ltd
- NorwayDaraprimGlaxoSmithKline
- GermanyDaraprimGlaxosmithkline Gmbh & Co. Kg
- BelgiumDaraprim 25 mgGlaxoSmithKline Pharmaceuticals
- FranceMALOCIDE 50 mg, compriméSANOFI WINTHROP INDUSTRIE
Authorised across Europe · EMA
The same active substance is authorised in 6 EEA countries. Names it is sold under:
- Belgium · Daraprim
- Germany · Daraprim
- Spain · Daraprim
- United Kingdom (Northern Ireland) · Daraprim
- Luxembourg · Daraprim
- Portugal · Pirimetamina Labesfal
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/972016f4-bfea-49e5-9973-7ba07808124a GET /v1/drugs/972016f4-bfea-49e5-9973-7ba07808124a?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tablet",
"route": "Oraal gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h00254_smpc.pdf",
"strength": null,
"atc_label": "Pyrimethamine",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg00254",
"excipients": [
"DOCUSAATNATRIUM",
"LACTOSE 1-WATER",
"MAGNESIUMSTEARAAT (E 470b)",
"MAÏSZETMEEL",
"STARCH, HYDROLYSED"
],
"substances": [
"PYRIMETHAMINE"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h00254.pdf",
"authorised_at": "1990/05/20",
"procedure_number": null,
"dispensing_status": "Uitsluitend recept",
"registration_number": "00254",
"additional_monitoring": "N"
}See everything about pyrimethamine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.