Germany· DE-A57-5d55850aca9281d3
Cliovelle
A medicinal product containing norethisterone acetate, estradiol valerate, registered in Germany by Besins Healthcare Germany Gmbh.
Checked against EMA Article 57 (European Union) on
Informational only — not a medical device.
The record
At a glance
EMA Article 57 (European Union)- Active substance
- Norethisterone Acetate, Estradiol Valerate
- Manufacturer
- Besins Healthcare Germany Gmbh
- Country
- Germany (DE)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- EMA Article 57 (European Union)
- Last checked
- September 30, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Norethisterone acetate, estradiol valerate in 13 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomClimesse tabletsNovartis Pharmaceuticals UK Ltd
- United StatesABIGALEXiromed LLC
- NorwayActivelleNovo Nordisk A/S
- SwitzerlandActivelle
- SwedenActivelle 1 mg/0,5 mg Filmdragerad tablettNovo Nordisk A/S
- PolandActivelleNovo Nordisk A/S
- IcelandActivelleNovo Nordisk A/S*
- SpainACTIVELLE 1 mg/0,5 mg COMPRIMIDOS RECUBIERTOS CON PELICULAIsdin S.A.
Authorised across Europe · EMA
The same active substance is authorised in 26 EEA countries. Names it is sold under:
- Austria · Activelle, Kliogest
- Belgium · Activelle, Activelle Minor
- Bulgaria · Активел, Трисеквенс
- Cyprus · Trisequens
- Czechia · Activelle, Kliogest
- Denmark · Activelle, Activelle Low
- Estonia · Activelle, Eviana
- Spain · Activelle, Duofemme
- Finland · Activelle, Cliovelle
- France · Activelle, Kliogest
- Greece · Trisequens
- Croatia · Activelle, Novofem
- Hungary · Activelle, Kliogest
- Ireland · Activelle, Kliogest
- Iceland · Activelle, Activelle Low
- Italy · Activelle
- Lithuania · Activelle, Kliogest
- Luxembourg · Activelle, Activelle Minor
- Latvia · Activelle, Kliogest
- Netherlands · Activelle
- Norway · Activelle, Cliovelle
- Poland · Cliovelle, Kliogest
- Portugal · Activelle, Kliogest
- Sweden · Activelle, Cliovelle
- Slovenia · Activelle, Kliogest
- Slovakia · Activelle, Novofem
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of EMA Article 57 (European Union). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/8e1ed612-139f-4f73-8061-5d41898c52af GET /v1/drugs/8e1ed612-139f-4f73-8061-5d41898c52af?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"pzn": null,
"route": "Oral Use",
"source": "ema_art57_de",
"ma_number": null,
"substance": "Norethisterone Acetate, Estradiol Valerate",
"atc_from_source": null,
"authorisation_country": "Germany"
}See everything about norethisterone acetate, estradiol valerate.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.