Poland· PL-100427020

APAP intense

A ibuprofen, kombinationen product containing ibuprofenum + paracetamolum, registered in Poland by US Pharmacia Sp. z o.o.. The same ATC class is registered in 9 of our 19 countries.

ATC M01AE51

Checked against URPL (Poland) on September 27, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about ibuprofenum + paracetamolumAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Ibuprofen, kombinationen is registered in 9 of 19 countries.

Countries holding a registration under ATC M01AE51 (ibuprofen, kombinationen), each read from that country’s own register.

This record: Poland, from URPL (Poland)
6 of them publish a price we can compare per daily dose

Search ibuprofen, kombinationen products by name

Ibuprofen, kombinationen · ATC M01AE51

9 / 19 countries

Belgiumprice
Canada
Czechiaprice
Finlandprice
Icelandprice
Ireland
Netherlands
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

URPL (Poland)

Active substance: Ibuprofenum + Paracetamolum
Manufacturer: US Pharmacia Sp. z o.o.
Country: Poland (PL)
ATC code: M01AE51
ATC class: Ibuprofen, Kombinationen
Reimbursed: Not published by this register
Source register: URPL (Poland)
Last checked: September 27, 2026

Packs & prices · 9

gtin
05909991430894
gtin
05909991430900
gtin
05909991430917
gtin
05909991430924
gtin
05909991430931
gtin
05909991430948
gtin
05909991430955
gtin
05909991430962
gtin
05909991430979

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

57 interactions on record for ibuprofen, kombinationen.

Mechanism, severity and management for each pair, from a commercially licensed source — included with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check ibuprofen, kombinationen against other medicines How interaction checks work

Ibuprofen, kombinationen · interactions on record

57 records

57 more interactions with mechanism and management, from a commercially licensed source.

Mechanism and what to do, in the interaction check

Interaction register. Grades as the source publishes them.

Same medicine, other countries

Ibuprofen, kombinationen in 14 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All ibuprofen, kombinationen products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Combogesic, Comboval
Belgium · Brufen Plus Paracetamol, Combogesic
Bulgaria · Lekadol Complex, Nurulin Duo
Cyprus · Duomax, Edolfen Dual Action
Czechia · Brufen Combi, Cetalgen
Germany · Comboval, Duoval
Denmark · Comboval, Doleron
Estonia · Combogesic, Kivenul
Spain · Antidol Dual, Comboval
Finland · Comboval, Dolerin
France · Cetafen, Paracetamol/Ibuprofene Medipha
United Kingdom (Northern Ireland) · Combogesic, Combogesic Iv
Greece · Algofren Compositum, Combogesic
Croatia · Blokmax Duo, Brufen Akut Duo
Hungary · Advil Duo, Combogesic
Ireland · Combileve, Combileve 500 Mg/200 Mg Film-Coated Tablets
Iceland · Comboval, Paracetamol/Ibuprofen Vale Pharma
Italy · Combogesic, Paracetamolo E Ibuprofene Mylan
Lithuania · Adobil, Combogesic
Luxembourg · Brufen Plus Paracetamol, Combogesic
Latvia · Adobil, Combogesic
Malta · Combofusiv, Duomax
Netherlands · Comboval, Nuralgan
Norway · Comboval, Dolerin
Portugal · Brufenon, Combofusiv
Romania · Advil Duo, Analgex
Sweden · Comboval, Dolerin
Slovenia · Adobil, Besta
Slovakia · Cetalgen, Combogesic

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of URPL (Poland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/8c40d521-5592-423f-98d5-66a2f62c2f29
GET /v1/drugs/8c40d521-5592-423f-98d5-66a2f62c2f29?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Tabletki powlekane",
  "source": "urpl",
  "strength": "200 mg + 500 mg",
  "packaging": "05909991430894 ¦ OTC ¦ 136492\n4 tabl.\n05909991430900 ¦ OTC ¦ 136493\n6 tabl.\n05909991430917 ¦ OTC ¦ 136494\n8 tabl.\n05909991430924 ¦ OTC ¦ 136495\n10 tabl.\n05909991430931 ¦ OTC ¦ 136496\n12 tabl.\n05909991430948 ¦ OTC ¦ 136497\n16 tabl.\n05909991430955 ¦ OTC ¦ 136498\n20 tabl.\n05909991430962 ¦ OTC ¦ 136499\n24 tabl.\n05909991430979 ¦ OTC ¦ 136500\n32 tabl.",
  "substance": "Ibuprofenum 200 mg + Paracetamolum 500 mg",
  "common_name": "Ibuprofenum + Paracetamolum",
  "pl_product_id": "100427020",
  "pozwolenie_nr": "25910",
  "auth_procedure": "DCP",
  "authorisation_validity": "Bezterminowe"
}

API reference MCP server Plans

See everything about ibuprofen, kombinationen.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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