Netherlands· NL-747a27bb458d

Leflunomide Tillomed 10 mg, tabletten

A leflunomide product containing leflunomide, registered in Netherlands by Tillomed Pharma GmbH. The same ATC class is registered in 15 of our 19 countries.

ATC L04AK01

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about leflunomideAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Leflunomide is registered in 15 of 19 countries.

Countries holding a registration under ATC L04AK01 (leflunomide), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
9 of them publish a price we can compare per daily dose

Search leflunomide products by name

Leflunomide · ATC L04AK01

15 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Germany
Icelandprice
Italyprice
Japan
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of leflunomide costs, country by country.

Normalised to the WHO defined daily dose (20 mg), the median price runs from $0.47 in United States to $2.13 in Italy — a ×4.5 gap.

3 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown
US figures are pharmacy acquisition cost (CMS NADAC), not retail

Open the full comparison — free account Drug prices for market access

Leflunomide · price per daily dose (20 mg)

USD · FX 28 Sept 2026

IT Italy$2.13
CH Switzerland$1.48
US United States$0.47 (acquisition cost)

Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: LEFLUNOMIDE
Manufacturer: Tillomed Pharma GmbH
Country: Netherlands (NL)
ATC code: L04AK01
ATC class: Leflunomide
Defined daily dose: 20 mg, O
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
124360

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

805 interactions on record for leflunomide.

Graded by severity as the source publishes them — 537 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check leflunomide against other medicines How interaction checks work

Leflunomide · interactions on record

805 records

537 severe
47 moderate
7 minor
214 info

Most severe, free to view

ClotrimazoleA01AB18severe
Chenodeoxycholic acidA05AA01severe
PrednisoloneA07EA01severe
HydrocortisoneA07EA02severe

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Leflunomide in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All leflunomide products

Authorised across Europe · EMA

The same active substance is authorised in 26 EEA countries. Names it is sold under:

Austria · Leflunomid Stada
Belgium · Leflunomid Sandoz, Leflunomide Ab
Bulgaria · Багеда
Cyprus · Arotan
Czechia · Leflon, Leflugen
Germany · Leflon, Leflunomid 1 A Pharma
Denmark · Leflunomid, Leflunomid "egis"
Estonia · Leflunomide Elvim
Spain · Lefluartil, Leflunomida Aurovitas
Finland · Leflunomide Orion, Leflunomide Stada
France · Leflunomide Arrow, Leflunomide Biogaran
United Kingdom (Northern Ireland) · Leflunomide Aspire Pharma, Leflunomide Milpharm
Greece · Lefid, Lefluonia
Hungary · Leflunomid Sandoz
Ireland · Leflunomide Aspire Pharma (Malta)
Iceland · Arava, Leflunomide Medac
Italy · Leflunomide Aurobindo, Leflunomide Mylan
Liechtenstein · Arava, Leflunomide Medac
Lithuania · Leflunomide Elvim, Leflunomide Sandoz
Latvia · Leflunomide Elvim, Leflunomide Sandoz
Malta · Leflunomide Normon
Norway · Arava, Leflunomide Medac
Poland · Leflunomid Bluefish, Leflunomid Egis
Portugal · Leflunomida Farmoz, Leflunomida Generis
Romania · Leflon, Leflunomidă Arena
Sweden · Leflunomid Bluefish

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/893e5cd0-344b-40eb-8e2f-255f67d87fe5
GET /v1/drugs/893e5cd0-344b-40eb-8e2f-255f67d87fe5?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Tablet",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h124360_smpc.pdf",
  "strength": null,
  "atc_label": "Leflunomide",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg124360",
  "excipients": [
    "CROSCARMELLOSE  NATRIUM  (E 468)",
    "LACTOSE 1-WATER",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MAÏSZETMEEL, GEPREGELATINEERD",
    "SILICIUMDIOXIDE (E 551)",
    "TALK (E 553b)"
  ],
  "substances": [
    "LEFLUNOMIDE"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h124360.pdf",
  "authorised_at": "2020/04/22",
  "procedure_number": "DE/H/6054/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "124360",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about leflunomide.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console