Ireland· IE-PA-PA22583/001/001
Rapifen 500 micrograms/ml solution for injection or infusion
A alfentanil product containing alfentanil hydrochloride, registered in Ireland by Piramal Critical Care B.V.. The same ATC class is registered in 12 of our 19 countries.
Checked against HPRA (Ireland) on
Informational only — not a medical device.
Where it is registered
Alfentanil is registered in 12 of 19 countries.
Countries holding a registration under ATC N01AH02 (alfentanil), each read from that country’s own register.
- This record: Ireland, from HPRA (Ireland)
- 6 of them publish a price we can compare per daily dose
Alfentanil · ATC N01AH02
12 / 19 countries
- Belgiumprice
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Ireland
- Netherlands
- Norwayprice
- Sweden
- Switzerlandprice
- United Kingdom
The record
At a glance
HPRA (Ireland)- Active substance
- ALFENTANIL HYDROCHLORIDE
- Manufacturer
- Piramal Critical Care B.V.
- Country
- Ireland (IE)
- ATC code
- N01AH02
- ATC class
- Alfentanil
- Reimbursed
- Not published by this register
- Source register
- HPRA (Ireland)
- Last checked
- September 28, 2026
Packs & prices · 1
- ie_pa_numberPA22583/001/001
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
240 interactions on record for alfentanil.
Graded by severity as the source publishes them — 41 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Alfentanil · interactions on record
240 records
- 41 severe
- 163 moderate
- 2 minor
- 34 info
Most severe, free to view
- ClotrimazoleA01AB18severe
- OndansetronA04AA01severe
- GranisetronA04AA02severe
- DolasetronA04AA04severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Alfentanil in 11 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- FinlandAlfentanil HamelnHameln Pharma GmbH
- BelgiumAlfentanil Kalceks 0.5 mg/mlKalceks
- NorwayAlfentanil KalceksAS Kalceks
- SwedenAlfentanil Kalceks 0,5 mg/ml Injektions-/infusionsvätska, lösningAS KALCEKS
- United KingdomAlfentanil 0.1% nasal spraySpecial Order
- SwitzerlandRapifen, Injektions-/InfusionslösungPiramal Critical Care Limited, London, Zweigniederlassung Rüschlikon
- CzechiaRAPIFENPiramal Critical Care B.V., Voorschoten
- NetherlandsAlfentanil Kalceks 0,5 mg/ml oplossing voor injectie/infusieAS Kalceks
Authorised across Europe · EMA
The same active substance is authorised in 17 EEA countries. Names it is sold under:
- Austria · Alfentanil Hameln, Rapifen
- Belgium · Alfentanil Kalceks, Rapifen
- Czechia · Rapifen
- Germany · Alfentanil Hameln, Alfentanil Kalceks
- Denmark · Alfentanil Hameln, Alfentanil Kalceks
- Spain · Limifen
- Finland · Alfentanil Hameln, Alfentanil Kalceks
- France · Alfentanil Kalceks, Rapifen
- United Kingdom (Northern Ireland) · Alfentanil Hameln, Alfentanil Hameln Pharma
- Italy · Alfentanil Piramal
- Luxembourg · Rapifen
- Latvia · Alfentanil Kalceks
- Malta · Alfentanil Kalceks
- Netherlands · Alfentanil Hameln, Alfentanil Kalceks
- Norway · Alfentanil Hameln, Alfentanil Kalceks
- Portugal · Alfentanilo Hameln, Alfentanilo Kalceks
- Sweden · Alfentanil Hameln, Alfentanil Kalceks
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/85187752-e7d0-4dc9-96c8-a3fc85f4e7bc GET /v1/drugs/85187752-e7d0-4dc9-96c8-a3fc85f4e7bc?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Solution for injection/infusion",
"routes": [
"Intravenous use"
],
"source": "hpra",
"atc_all": [
"N01AH",
"N01AH02"
],
"strength": null,
"pa_number": "PA22583/001/001",
"substances": [
"ALFENTANIL HYDROCHLORIDE"
],
"legal_basis": "Full application (Article 8(3) of Directive No 2001/83/EC)",
"market_info": "Not marketed",
"authorised_at": "09/06/1992",
"dispensing_status": "Product subject to prescription which may not be renewed (A)",
"registration_status": "AU",
"supply_legal_status": "Supply through pharmacies only",
"interchangeable_code": null
}See everything about alfentanil.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.