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France· FR:66898948

SIKLOS 1000 mg, comprimé pelliculé sécable

A hydroxycarbamide product containing hydroxycarbamide, registered in France by THERAVIA, on the national reimbursement list. The same ATC class is registered in 16 of our 19 countries.

Reimbursed in France (Assurance maladie)ATC L01XX05

Checked against Base de données publique des médicaments — BDPM (France) on

Informational only — not a medical device.

SOURCE REGISTER · FRBase de données publique des médicament…normalisedSIKLOS 1000 mg, comprimé pelliculé sé…ATCL01XX05REGISTER NO.FR:66898948PACKS LISTED1CHECKEDSeptember 12, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about hydroxycarbamideAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Hydroxycarbamide is registered in 16 of 19 countries.

Countries holding a registration under ATC L01XX05 (hydroxycarbamide), each read from that country’s own register.

  • This record: France, from Base de données publique des médicaments — BDPM (France)
  • 10 of them publish a price we can compare per daily dose
Search hydroxycarbamide products by name

Hydroxycarbamide · ATC L01XX05

16 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Franceprice
  • Germany
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of hydroxycarbamide costs, country by country.

Normalised to the WHO defined daily dose (1.4 g), the median price runs from $0.51 in United States to $16.83 in France — a ×33 gap.

  • France: $16.83 per daily dose (median across products in the class)
  • Public list prices, converted to USD at the rate date shown
  • US figures are pharmacy acquisition cost (CMS NADAC), not retail
Open the full comparison — free accountDrug prices for market access

Hydroxycarbamide · price per daily dose (1.4 g)

USD · FX 28 Sept 2026

  • FR France$16.83
  • CH Switzerland$2.74
  • IT Italy$1.13
  • US United States$0.51 (acquisition cost)
Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

Base de données publique des médicaments — BDPM (France)
Active substance
HYDROXYCARBAMIDE
Manufacturer
THERAVIA
Country
France (FR)
ATC code
L01XX05
ATC class
Hydroxycarbamide
Defined daily dose
1.4 g, O
Reimbursed
Yes
Source register
Base de données publique des médicaments — BDPM (France)
Last checked
September 12, 2026

Packs & prices · 1

1 priced
  • cip13
    3400938101942
    flacon(s) polyéthylène haute densité (PEHD) avec fermeture de sécurité enfant de 30 comprimé(s)
    EUR 315.6

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

333 interactions on record for hydroxycarbamide.

Graded by severity as the source publishes them — 31 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check hydroxycarbamide against other medicinesHow interaction checks work

Hydroxycarbamide · interactions on record

333 records

  • 31 severe
  • 101 moderate
  • 15 minor
  • 186 info

Most severe, free to view

  • DidanosineJ05AF02severe
  • CladribineL01BB04severe
  • Talimogene laherparepvecL01XL02severe
  • Talimogen laherparepvecL01XX51severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Hydroxycarbamide in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All hydroxycarbamide products

Authorised across Europe · EMA

The same active substance is authorised in 30 EEA countries. Names it is sold under:

  • Austria · Ardjaq, Hydroxycarbamid Devatis
  • Belgium · Hydrea
  • Bulgaria · Хидреа
  • Cyprus · Hydreasyn
  • Czechia · Litalir
  • Germany · Ardjaq, Hydroxycarbamid 1 A Pharma
  • Denmark · Hydroxyurea Medac, Oribamide
  • Estonia · Hydrea
  • Spain · Hidroxicarbamida Hikma, Hidroxicarbamida Medac
  • Finland · Hydrea, Hydroxyurea Medac
  • United Kingdom (Northern Ireland) · Hydrea, Hydroxycarbamide
  • Greece · Hydreasyn
  • Croatia · Litalir, Xybaid
  • Hungary · Hydroxycarbamide Pharmacenter, Litalir
  • Ireland · Hydrea
  • Iceland · Hydroxyurea Medac, Siklos
  • Italy · Idrossicarbamide Aurobindo, Onco Carbide
  • Liechtenstein · Siklos
  • Lithuania · Hydrea
  • Luxembourg · Hydrea, Hydroxycarbamid Devatis
  • Latvia · Hydrea
  • Malta · Hydroxycarbamide Eugia
  • Netherlands · Hydroxycarbamide Devatis, Hydroxycarbamide Eugia
  • Norway · Hydroxyurea Medac, Oribamide
  • Poland · Hydroxycarbamid Eugia, Hydroxycarbamid Teva
  • Portugal · Hidroxicarbamida Generis, Hidroxicarbamida Hikma
  • Romania · Hydrea
  • Sweden · Hydrea, Hydroxyurea Medac
  • Slovenia · Hidroksisečnina Aptapharma, Litalir
  • Slovakia · Hydroxykarbamid Medac, Xybaid

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Base de données publique des médicaments — BDPM (France). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/81ee35c6-7dd3-476b-b1d8-ca3b6e4c03ab
GET /v1/drugs/81ee35c6-7dd3-476b-b1d8-ca3b6e4c03ab?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "cis": "66898948",
  "date_amm": "2007-06-29",
  "type_amm": "Procédure centralisée",
  "numero_ue": "EU/1/07/397",
  "substance": "HYDROXYCARBAMIDE",
  "atc_source": "fr_atc_restore_2026-09-06",
  "statut_amm": "Autorisation active",
  "statut_bdm": null,
  "forme_pharmaceutique": "comprimé pelliculé sécable",
  "voies_administration": "orale",
  "etat_commercialisation": "Commercialisée",
  "surveillance_renforcee": "Non"
}
API referenceMCP serverPlans

See everything about hydroxycarbamide.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console