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Italy· 040107082

DAXAS*28 compresse 250 mcg

A roflumilast product containing roflumilast, registered in Italy by ASTRAZENECA AB, on the national reimbursement list. The same ATC class is registered in 12 of our 19 countries.

Reimbursed in Italy (AIFA class A)ATC R03DX07

Checked against the register on

Informational only — not a medical device.

SOURCE REGISTER · ITPublic registernormalisedDAXAS*28 compresse 250 mcgATCR03DX07REGISTER NO.040107082PACKS LISTED1CHECKEDJune 4, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about roflumilastAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Roflumilast is registered in 12 of 19 countries.

Countries holding a registration under ATC R03DX07 (roflumilast), each read from that country’s own register.

  • This record: Italy
  • 8 of them publish a price we can compare per daily dose
Search roflumilast products by name

Roflumilast · ATC R03DX07

12 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of roflumilast costs, country by country.

Normalised to the WHO defined daily dose (0.5 mg), so markets compare like for like.

  • Italy: $2.50 per daily dose (median across products in the class)
  • Public list prices, converted to USD at the rate date shown
Open the full comparison — free accountDrug prices for market access

Roflumilast · price per daily dose (0.5 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$3.02
  • IT Italy$2.50
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

Active substance
Roflumilast
Manufacturer
ASTRAZENECA AB
Country
Italy (IT)
ATC code
R03DX07
ATC class
Roflumilast
Defined daily dose
0.5 mg, O
Reimbursed
Yes
Last checked
June 4, 2026

Packs & prices · 1

1 priced
  • aic
    040107082
    DAXAS*28 compresse 250 mcg
    EUR 30.73

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

352 interactions on record for roflumilast.

Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check roflumilast against other medicinesHow interaction checks work

Roflumilast · interactions on record

352 records

  • 2 severe
  • 347 moderate
  • 3 minor

Most severe, free to view

  • CladribineL01BB04severe
  • CimetidineA02BA01moderate
  • Obeticholic acidA05AA04moderate
  • PrednisoloneA07EA01moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Roflumilast in 15 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All roflumilast products

Authorised across Europe · EMA

The same active substance is authorised in 15 EEA countries. Names it is sold under:

  • Austria · Rofluma, Roflumilast Accord
  • Cyprus · Damirast
  • Czechia · Rumixafen
  • Germany · Roflum Hexal, Roflumila Puren
  • Denmark · Firekol
  • Spain · Roflumilast Aurovitas
  • Finland · Firekol
  • United Kingdom (Northern Ireland) · Roflumilast Milpharm, Roflumilast Torrent Pharma (Uk)
  • Greece · Damirast
  • Iceland · Daxas
  • Liechtenstein · Daxas
  • Norway · Daxas, Firekol
  • Portugal · Roflumilaste Generis
  • Sweden · Firekol, Roflumilast Accord
  • Slovakia · Rumixafen

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of the issuing authority. This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/7c06f203-1c9c-4499-9a90-7d4529a75096
GET /v1/drugs/7c06f203-1c9c-4499-9a90-7d4529a75096?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "price": 30.73,
  "source": "aifa",
  "currency": "EUR",
  "strength": "ROFLUMILAST 250MCG 28 UNITA' USO ORALE",
  "substance": "Roflumilast",
  "equivalence_group": "RFB",
  "transparency_flag": null
}
API referenceMCP serverPlans

See everything about roflumilast.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console