United States· US:71321-501_9c1ede62-fd47-41f4-96da-93d65133042d
Theophylline
A theophylline product containing theophylline anhydrous, registered in United States by Brandywine Pharmaceuticals, LLC. The same ATC class is registered in 12 of our 19 countries.
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
Where it is registered
Theophylline is registered in 12 of 19 countries.
Countries holding a registration under ATC R03DA04 (theophylline), each read from that country’s own register.
- This record: United States, from FDA National Drug Code directory (United States)
- 6 of them publish a price we can compare per daily dose
Theophylline · ATC R03DA04
12 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Ireland
- Japan
- Norwayprice
- Polandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of theophylline costs, country by country.
Normalised to the WHO defined daily dose (0.4 g), so markets compare like for like.
- United States: $0.71 per daily dose (median across products in the class)
- Public list prices, converted to USD at the rate date shown
Theophylline · price per daily dose (0.4 g)
USD · FX 28 Sept 2026
- US United States$0.71 (acquisition cost)
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- THEOPHYLLINE ANHYDROUS
- Manufacturer
- Brandywine Pharmaceuticals, LLC
- Country
- United States (US)
- ATC code
- R03DA04
- ATC class
- Theophylline
- Defined daily dose
- 0.4 g, O
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- July 26, 2026
Packs & prices · 2
- ndc117132150110100 TABLET, EXTENDED RELEASE in 1 BOTTLE (71321-501-10)
- ndc1171321-501-10
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
438 interactions on record for theophylline.
Graded by severity as the source publishes them — 34 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Theophylline · interactions on record
438 records
- 34 severe
- 222 moderate
- 45 minor
- 132 info
Most severe, free to view
- MexiletineC01BB02severe
- RiociguatC02KX05severe
- PindololC07AA03severe
- PropranololC07AA05severe
5 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Theophylline in 13 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- NorwayTeofyllin Aurora Medical2care4 ApS
- FinlandRetafyllinOrion Corporation
- United KingdomTheo-Dur 200mg tabletsAstraZeneca UK Ltd
- IrelandUNIPHYLLIN 200 mg Prolonged-Release TabletsEnnogen Healthcare (Europe) Limited
- BelgiumPediaphyllin 200 mgLaboratoires S.M.B.
- SwedenTheo-Dur 200 mg DepottablettKaro Pharma AB
- CanadaAA-THEO LAAA PHARMA INC
- SpainTHEO-DUR 200 mg COMPRIMIDOS DE LIBERACION PROLONGADAVegal Farmaceutica S.L.
Authorised across Europe · EMA
The same active substance is authorised in 26 EEA countries. Names it is sold under:
- Austria · Theospirex, Theospirex Retard
- Belgium · Xanthium
- Bulgaria · Теотард
- Cyprus · Theo-Dur
- Czechia · Euphyllin Cr N
- Germany · Afpred Forte-Theo, Bronchoretard
- Denmark · Theo-Dur, Unixan
- Estonia · Teotard
- Spain · Elixifilin, Teromol Retard
- Finland · Retafyllin
- France · Dilatrane, Tedralan
- United Kingdom (Northern Ireland) · Uniphyllin
- Greece · Theo-Bros, Theo-Dur
- Croatia · Teotard
- Hungary · Theophyllini Fono Vii. Naturland, Theophyllini Fono Viii. Parma
- Ireland · Uniphyllin
- Lithuania · Teotard
- Luxembourg · Xanthium
- Latvia · Teotard
- Norway · Theo-Dur
- Poland · Euphyllin Long, Theophyllinum Tramco
- Portugal · Unicontin
- Romania · Teotard
- Sweden · Theo-Dur
- Slovenia · Teotard
- Slovakia · Euphyllin Cr N 200, Euphyllin Cr N 300
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/767d83ed-00e7-4b20-b77d-cf44fc6bf73d GET /v1/drugs/767d83ed-00e7-4b20-b77d-cf44fc6bf73d?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"route": "ORAL",
"source": "ndc",
"strength": "200",
"substance": "THEOPHYLLINE ANHYDROUS",
"productndc": "71321-501",
"dosage_form": "TABLET, EXTENDED RELEASE",
"dea_schedule": null,
"strength_unit": "mg/1",
"application_number": "ANDA087400",
"marketing_category": "ANDA"
}See everything about theophylline.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.